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Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial

BACKGROUND: Comprehensive geriatric assessment provided in hospital wards in frail patients admitted to hospital has been shown to reduce mortality and increase the likelihood of living at home later. Systematic geriatric assessment provided in emergency departments (ED) may be effective for reducin...

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Autores principales: Alakare, Janne, Kemp, Kirsi, Strandberg, Timo, Castrén, Maaret, Jakovljević, Dimitrije, Tolonen, Jukka, Harjola, Veli-Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252275/
https://www.ncbi.nlm.nih.gov/pubmed/34215193
http://dx.doi.org/10.1186/s12877-021-02351-2
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author Alakare, Janne
Kemp, Kirsi
Strandberg, Timo
Castrén, Maaret
Jakovljević, Dimitrije
Tolonen, Jukka
Harjola, Veli-Pekka
author_facet Alakare, Janne
Kemp, Kirsi
Strandberg, Timo
Castrén, Maaret
Jakovljević, Dimitrije
Tolonen, Jukka
Harjola, Veli-Pekka
author_sort Alakare, Janne
collection PubMed
description BACKGROUND: Comprehensive geriatric assessment provided in hospital wards in frail patients admitted to hospital has been shown to reduce mortality and increase the likelihood of living at home later. Systematic geriatric assessment provided in emergency departments (ED) may be effective for reducing days in hospital and unnecessary hospital admissions, but this has not yet been proven in randomised trials. METHODS: We conducted a single-centre, randomised controlled trial with a parallel-group, superiority design in an academic hospital ED. ED patients aged ≥ 75 years who were frail, or at risk of frailty, as defined by the Clinical Frailty Scale, were included in the trial. Patients were recruited during the period between December 11, 2018 and June 7, 2019, and followed up for 365 days. For the intervention group, systematic geriatric assessment was added to their standard care in the ED, whereas the control group received standard care only. The primary outcome was cumulative hospital stay during 365-day follow-up. The secondary outcomes included: admission rate from the index visit, total hospital admissions, ED-readmissions, proportion of patients living at home at 365 days, 365-day mortality, and fall-related ED-visits. RESULTS: A total of 432 patients, 63 % female, with median age of 85 years, formed the analytic sample of 213 patients in the intervention group and 219 patients in the control group. Cumulative hospital stay during one-year follow-up as rate per 100 person-years for the intervention and control groups were: 3470 and 3149 days, respectively, with rate ratio of 1.10 (95 % confidence interval, 0.55–2.19, P = .78). Admission rates to hospital wards from the index ED visit for the intervention and control groups were: 62 and 70 %, respectively (P = .10). No significant differences were observed between the groups for any outcomes. CONCLUSION: Systematic geriatric assessment for older adults with frailty in the ED did not reduce hospital stay during one-year follow-up. No statistically significant difference was observed for any secondary outcomes. More coordinated, continuous interventions should be tested for potential benefits in long-term outcomes. TRIAL REGISTRATION: The trial was registered in the ClinicalTrials.gov (registration number and date NCT03751319 23/11/2018).
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spelling pubmed-82522752021-07-06 Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial Alakare, Janne Kemp, Kirsi Strandberg, Timo Castrén, Maaret Jakovljević, Dimitrije Tolonen, Jukka Harjola, Veli-Pekka BMC Geriatr Research BACKGROUND: Comprehensive geriatric assessment provided in hospital wards in frail patients admitted to hospital has been shown to reduce mortality and increase the likelihood of living at home later. Systematic geriatric assessment provided in emergency departments (ED) may be effective for reducing days in hospital and unnecessary hospital admissions, but this has not yet been proven in randomised trials. METHODS: We conducted a single-centre, randomised controlled trial with a parallel-group, superiority design in an academic hospital ED. ED patients aged ≥ 75 years who were frail, or at risk of frailty, as defined by the Clinical Frailty Scale, were included in the trial. Patients were recruited during the period between December 11, 2018 and June 7, 2019, and followed up for 365 days. For the intervention group, systematic geriatric assessment was added to their standard care in the ED, whereas the control group received standard care only. The primary outcome was cumulative hospital stay during 365-day follow-up. The secondary outcomes included: admission rate from the index visit, total hospital admissions, ED-readmissions, proportion of patients living at home at 365 days, 365-day mortality, and fall-related ED-visits. RESULTS: A total of 432 patients, 63 % female, with median age of 85 years, formed the analytic sample of 213 patients in the intervention group and 219 patients in the control group. Cumulative hospital stay during one-year follow-up as rate per 100 person-years for the intervention and control groups were: 3470 and 3149 days, respectively, with rate ratio of 1.10 (95 % confidence interval, 0.55–2.19, P = .78). Admission rates to hospital wards from the index ED visit for the intervention and control groups were: 62 and 70 %, respectively (P = .10). No significant differences were observed between the groups for any outcomes. CONCLUSION: Systematic geriatric assessment for older adults with frailty in the ED did not reduce hospital stay during one-year follow-up. No statistically significant difference was observed for any secondary outcomes. More coordinated, continuous interventions should be tested for potential benefits in long-term outcomes. TRIAL REGISTRATION: The trial was registered in the ClinicalTrials.gov (registration number and date NCT03751319 23/11/2018). BioMed Central 2021-07-02 /pmc/articles/PMC8252275/ /pubmed/34215193 http://dx.doi.org/10.1186/s12877-021-02351-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Alakare, Janne
Kemp, Kirsi
Strandberg, Timo
Castrén, Maaret
Jakovljević, Dimitrije
Tolonen, Jukka
Harjola, Veli-Pekka
Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title_full Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title_fullStr Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title_full_unstemmed Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title_short Systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
title_sort systematic geriatric assessment for older patients with frailty in the emergency department: a randomised controlled trial
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252275/
https://www.ncbi.nlm.nih.gov/pubmed/34215193
http://dx.doi.org/10.1186/s12877-021-02351-2
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