Enantioselective Copper‐Catalyzed Borylative Cyclization for the Synthesis of Quinazolinones

Quinazolinones are common substructures in molecules of medicinal importance. We report an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged pyrroloquinazolinone motifs. The reaction proceeds with high enantio‐ and diastereocontrol, and can deliver products cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Dherbassy, Quentin, Manna, Srimanta, Shi, Chunling, Prasitwatcharakorn, Watcharapon, Crisenza, Giacomo E. M., Perry, Gregory J. P., Procter, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252434/
https://www.ncbi.nlm.nih.gov/pubmed/33847459
http://dx.doi.org/10.1002/anie.202103259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252434/
https://www.ncbi.nlm.nih.gov/pubmed/33847459
http://dx.doi.org/10.1002/anie.202103259

Ejemplares similares