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The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction

BACKGROUND: J‐waves and fragmented QRS (fQRS) on surface ECGs have been associated with the occurrence of ventricular tachyarrhythmias. Whether these non‐invasive parameters can also predict ventricular tachycardia (VT) recurrence after radiofrequency catheter ablation (RFCA) is unknown. Of interest...

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Autores principales: Naruse, Yoshihisa, de Riva, Marta, Watanabe, Masaya, Wijnmaalen, Adrianus P., Venlet, Jeroen, Timmer, Marnix, Schalij, Martin J., Zeppenfeld, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252510/
https://www.ncbi.nlm.nih.gov/pubmed/33624326
http://dx.doi.org/10.1111/pace.14203
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author Naruse, Yoshihisa
de Riva, Marta
Watanabe, Masaya
Wijnmaalen, Adrianus P.
Venlet, Jeroen
Timmer, Marnix
Schalij, Martin J.
Zeppenfeld, Katja
author_facet Naruse, Yoshihisa
de Riva, Marta
Watanabe, Masaya
Wijnmaalen, Adrianus P.
Venlet, Jeroen
Timmer, Marnix
Schalij, Martin J.
Zeppenfeld, Katja
author_sort Naruse, Yoshihisa
collection PubMed
description BACKGROUND: J‐waves and fragmented QRS (fQRS) on surface ECGs have been associated with the occurrence of ventricular tachyarrhythmias. Whether these non‐invasive parameters can also predict ventricular tachycardia (VT) recurrence after radiofrequency catheter ablation (RFCA) is unknown. Of interest, patients with a wide QRS‐complex have been excluded from clinical studies on J‐waves, although a J‐wave like pattern has been described for wide QRS. METHODS: We retrospectively included 168 patients (67 ± 10 years; 146 men) who underwent RFCA of post‐infarct VT. J‐wave pattern were defined as J‐point elevation ≥ 0.1 mV in at least two leads irrespective of QRS width. fQRS was defined as various RSR` pattern in patients with narrow QRS and more than two R wave in those with wide QRS. The primary endpoint was VT recurrence after RFCA up to 24 months. RESULTS: J‐wave pattern and fQRS were present in 27 and 28 patients, respectively. Overlap of J‐wave pattern and fQRS was observed in nine. During a median follow‐up of 20 (interquartile range 9–24) months, 46 (27%) patients had VT recurrence. Kaplan–Meier curves revealed that both J‐wave pattern and fQRS were associated with VT recurrence. Multivariate Cox regression analysis demonstrated that the presence of J‐wave pattern (hazard ratio [HR] 2.84; 95% confidence interval [CI] 1.45–5.58; P = .002) and greater number of induced VT (HR 1.29; 95% CI 1.15–1.45; P < .001) were the independent predictors of VT recurrence. CONCLUSIONS: A J‐wave pattern—but not fQRS—is independently associated with an increased risk of post‐infarct VT recurrence after RFCA irrespective of QRS width. This simple non‐invasive parameter may identify patients who require additional treatment.
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spelling pubmed-82525102021-07-09 The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction Naruse, Yoshihisa de Riva, Marta Watanabe, Masaya Wijnmaalen, Adrianus P. Venlet, Jeroen Timmer, Marnix Schalij, Martin J. Zeppenfeld, Katja Pacing Clin Electrophysiol Electrophysiology BACKGROUND: J‐waves and fragmented QRS (fQRS) on surface ECGs have been associated with the occurrence of ventricular tachyarrhythmias. Whether these non‐invasive parameters can also predict ventricular tachycardia (VT) recurrence after radiofrequency catheter ablation (RFCA) is unknown. Of interest, patients with a wide QRS‐complex have been excluded from clinical studies on J‐waves, although a J‐wave like pattern has been described for wide QRS. METHODS: We retrospectively included 168 patients (67 ± 10 years; 146 men) who underwent RFCA of post‐infarct VT. J‐wave pattern were defined as J‐point elevation ≥ 0.1 mV in at least two leads irrespective of QRS width. fQRS was defined as various RSR` pattern in patients with narrow QRS and more than two R wave in those with wide QRS. The primary endpoint was VT recurrence after RFCA up to 24 months. RESULTS: J‐wave pattern and fQRS were present in 27 and 28 patients, respectively. Overlap of J‐wave pattern and fQRS was observed in nine. During a median follow‐up of 20 (interquartile range 9–24) months, 46 (27%) patients had VT recurrence. Kaplan–Meier curves revealed that both J‐wave pattern and fQRS were associated with VT recurrence. Multivariate Cox regression analysis demonstrated that the presence of J‐wave pattern (hazard ratio [HR] 2.84; 95% confidence interval [CI] 1.45–5.58; P = .002) and greater number of induced VT (HR 1.29; 95% CI 1.15–1.45; P < .001) were the independent predictors of VT recurrence. CONCLUSIONS: A J‐wave pattern—but not fQRS—is independently associated with an increased risk of post‐infarct VT recurrence after RFCA irrespective of QRS width. This simple non‐invasive parameter may identify patients who require additional treatment. John Wiley and Sons Inc. 2021-03-09 2021-04 /pmc/articles/PMC8252510/ /pubmed/33624326 http://dx.doi.org/10.1111/pace.14203 Text en © 2021 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Electrophysiology
Naruse, Yoshihisa
de Riva, Marta
Watanabe, Masaya
Wijnmaalen, Adrianus P.
Venlet, Jeroen
Timmer, Marnix
Schalij, Martin J.
Zeppenfeld, Katja
The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title_full The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title_fullStr The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title_full_unstemmed The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title_short The prognostic value of J‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
title_sort prognostic value of j‐wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction
topic Electrophysiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252510/
https://www.ncbi.nlm.nih.gov/pubmed/33624326
http://dx.doi.org/10.1111/pace.14203
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