Cargando…
Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling
Protein complexes are defined by the three‐dimensional structure of participating binding partners. Knowledge about these structures can facilitate the design of peptidomimetics which have been applied for example, as inhibitors of protein–protein interactions (PPIs). Even though β‐sheets participat...
Autores principales: | Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina‐Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez‐Chantada, Mercedes, Chiarparin, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252567/ https://www.ncbi.nlm.nih.gov/pubmed/33783110 http://dx.doi.org/10.1002/anie.202102082 |
Ejemplares similares
-
Synthetic Amphipathic β-Sheet Temporin-Derived Peptide with Dual Antibacterial and Anti-Inflammatory Activities
por: Bellavita, Rosa, et al.
Publicado: (2022) -
Bicyclic
Engineered Sortase A Performs Transpeptidation
under Denaturing Conditions
por: Kiehstaller, Sebastian, et al.
Publicado: (2023) -
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
por: Adihou, Hélène, et al.
Publicado: (2020) -
In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme
por: Pelay‐Gimeno, Marta, et al.
Publicado: (2018) -
Targeted Recombinant Fusion Proteins of IFNγ and Mimetic IFNγ with PDGFβR Bicyclic Peptide Inhibits Liver Fibrogenesis In Vivo
por: Bansal, Ruchi, et al.
Publicado: (2014)