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3D amplified MRI (aMRI)

PURPOSE: Amplified MRI (aMRI) has been introduced as a new method of detecting and visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D aMRI approach. METHODS: 3D aMRI was developed and tested for its ability to amplify sub‐voxel motion in all three directions. I...

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Autores principales: Terem, Itamar, Dang, Leo, Champagne, Allen, Abderezaei, Javid, Pionteck, Aymeric, Almadan, Zainab, Lydon, Anna‐Maria, Kurt, Mehmet, Scadeng, Miriam, Holdsworth, Samantha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252598/
https://www.ncbi.nlm.nih.gov/pubmed/33949713
http://dx.doi.org/10.1002/mrm.28797
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author Terem, Itamar
Dang, Leo
Champagne, Allen
Abderezaei, Javid
Pionteck, Aymeric
Almadan, Zainab
Lydon, Anna‐Maria
Kurt, Mehmet
Scadeng, Miriam
Holdsworth, Samantha J.
author_facet Terem, Itamar
Dang, Leo
Champagne, Allen
Abderezaei, Javid
Pionteck, Aymeric
Almadan, Zainab
Lydon, Anna‐Maria
Kurt, Mehmet
Scadeng, Miriam
Holdsworth, Samantha J.
author_sort Terem, Itamar
collection PubMed
description PURPOSE: Amplified MRI (aMRI) has been introduced as a new method of detecting and visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D aMRI approach. METHODS: 3D aMRI was developed and tested for its ability to amplify sub‐voxel motion in all three directions. In addition, 3D aMRI was qualitatively compared to 2D aMRI on multi‐slice and 3D (volumetric) balanced steady‐state free precession cine data and phase contrast (PC‐MRI) acquired on healthy volunteers at 3T. Optical flow maps and 4D animations were produced from volumetric 3D aMRI data. RESULTS: 3D aMRI exhibits better image quality and fewer motion artifacts compared to 2D aMRI. The tissue motion was seen to match that of PC‐MRI, with the predominant brain tissue displacement occurring in the cranial‐caudal direction. Optical flow maps capture the brain tissue motion and display the physical change in shape of the ventricles by the relative movement of the surrounding tissues. The 4D animations show the complete brain tissue and cerebrospinal fluid (CSF) motion, helping to highlight the “piston‐like” motion of the ventricles. CONCLUSIONS: Here, we introduce a novel 3D aMRI approach that enables one to visualize amplified cardiac‐ and CSF‐induced brain motion in striking detail. 3D aMRI captures brain motion with better image quality than 2D aMRI and supports a larger amplification factor. The optical flow maps and 4D animations of 3D aMRI may open up exciting applications for neurological diseases that affect the biomechanics of the brain and brain fluids.
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spelling pubmed-82525982021-07-09 3D amplified MRI (aMRI) Terem, Itamar Dang, Leo Champagne, Allen Abderezaei, Javid Pionteck, Aymeric Almadan, Zainab Lydon, Anna‐Maria Kurt, Mehmet Scadeng, Miriam Holdsworth, Samantha J. Magn Reson Med Full Papers—Computer Processing and Modeling PURPOSE: Amplified MRI (aMRI) has been introduced as a new method of detecting and visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D aMRI approach. METHODS: 3D aMRI was developed and tested for its ability to amplify sub‐voxel motion in all three directions. In addition, 3D aMRI was qualitatively compared to 2D aMRI on multi‐slice and 3D (volumetric) balanced steady‐state free precession cine data and phase contrast (PC‐MRI) acquired on healthy volunteers at 3T. Optical flow maps and 4D animations were produced from volumetric 3D aMRI data. RESULTS: 3D aMRI exhibits better image quality and fewer motion artifacts compared to 2D aMRI. The tissue motion was seen to match that of PC‐MRI, with the predominant brain tissue displacement occurring in the cranial‐caudal direction. Optical flow maps capture the brain tissue motion and display the physical change in shape of the ventricles by the relative movement of the surrounding tissues. The 4D animations show the complete brain tissue and cerebrospinal fluid (CSF) motion, helping to highlight the “piston‐like” motion of the ventricles. CONCLUSIONS: Here, we introduce a novel 3D aMRI approach that enables one to visualize amplified cardiac‐ and CSF‐induced brain motion in striking detail. 3D aMRI captures brain motion with better image quality than 2D aMRI and supports a larger amplification factor. The optical flow maps and 4D animations of 3D aMRI may open up exciting applications for neurological diseases that affect the biomechanics of the brain and brain fluids. John Wiley and Sons Inc. 2021-05-05 2021-09 /pmc/articles/PMC8252598/ /pubmed/33949713 http://dx.doi.org/10.1002/mrm.28797 Text en © 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Full Papers—Computer Processing and Modeling
Terem, Itamar
Dang, Leo
Champagne, Allen
Abderezaei, Javid
Pionteck, Aymeric
Almadan, Zainab
Lydon, Anna‐Maria
Kurt, Mehmet
Scadeng, Miriam
Holdsworth, Samantha J.
3D amplified MRI (aMRI)
title 3D amplified MRI (aMRI)
title_full 3D amplified MRI (aMRI)
title_fullStr 3D amplified MRI (aMRI)
title_full_unstemmed 3D amplified MRI (aMRI)
title_short 3D amplified MRI (aMRI)
title_sort 3d amplified mri (amri)
topic Full Papers—Computer Processing and Modeling
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252598/
https://www.ncbi.nlm.nih.gov/pubmed/33949713
http://dx.doi.org/10.1002/mrm.28797
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