Vasculo‐toxic and pro‐inflammatory action of unbound haemoglobin, haem and iron in transfusion‐dependent patients with haemolytic anaemias

Increasing evidence suggests that free haem and iron exert vasculo‐toxic and pro‐inflammatory effects by activating endothelial and immune cells. In the present retrospective study, we compared serum samples from transfusion‐dependent patients with β‐thalassaemia major and intermedia, hereditary sph...

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Detalles Bibliográficos
Autores principales: Vinchi, Francesca, Sparla, Richard, Passos, Sara T., Sharma, Richa, Vance, S. Zebulon, Zreid, Hala S., Juaidi, Hesham, Manwani, Deepa, Yazdanbakhsh, Karina, Nandi, Vijay, Silva, André M. N., Agarvas, Anand R., Fibach, Eitan, Belcher, John D., Vercellotti, Gregory M., Ghoti, Husam, Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Red Cells and Iron
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252605/
https://www.ncbi.nlm.nih.gov/pubmed/33723861
http://dx.doi.org/10.1111/bjh.17361

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