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Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis

BACKGROUND: In this systematic review, we aim to identify prognostic imaging variables of recurrent laryngeal or hypopharyngeal carcinoma after chemoradiotherapy. METHODS: A systematic search was performed in PubMed and EMBASE (1990–2020). The crude data and effect estimates were extracted for each...

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Autores principales: Smits, Hilde J. G., Assili, Sanam, Kauw, Frans, Philippens, Marielle E. P., de Bree, Remco, Dankbaar, Jan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252607/
https://www.ncbi.nlm.nih.gov/pubmed/33797818
http://dx.doi.org/10.1002/hed.26698
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author Smits, Hilde J. G.
Assili, Sanam
Kauw, Frans
Philippens, Marielle E. P.
de Bree, Remco
Dankbaar, Jan W.
author_facet Smits, Hilde J. G.
Assili, Sanam
Kauw, Frans
Philippens, Marielle E. P.
de Bree, Remco
Dankbaar, Jan W.
author_sort Smits, Hilde J. G.
collection PubMed
description BACKGROUND: In this systematic review, we aim to identify prognostic imaging variables of recurrent laryngeal or hypopharyngeal carcinoma after chemoradiotherapy. METHODS: A systematic search was performed in PubMed and EMBASE (1990–2020). The crude data and effect estimates were extracted for each imaging variable. The level of evidence of each variable was assessed and pooled risk ratios (RRs) were calculated. RESULTS: Twenty‐two articles were included in this review, 17 on computed tomography (CT) and 5 on magnetic resonance imaging (MRI) variables. We found strong evidence for the prognostic value of tumor volume at various cut‐off points (pooled RRs ranging from 2.09 to 3.03). Anterior commissure involvement (pooled RR 2.19), posterior commissure involvement (pooled RR 2.44), subglottic extension (pooled RR 2.25), and arytenoid cartilage extension (pooled RR 2.10) were also strong prognostic factors. CONCLUSION: Pretreatment tumor volume and involvement of several subsites are prognostic factors for recurrent laryngeal or hypopharyngeal carcinoma after chemoradiotherapy.
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spelling pubmed-82526072021-07-09 Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis Smits, Hilde J. G. Assili, Sanam Kauw, Frans Philippens, Marielle E. P. de Bree, Remco Dankbaar, Jan W. Head Neck Clinical Reviews BACKGROUND: In this systematic review, we aim to identify prognostic imaging variables of recurrent laryngeal or hypopharyngeal carcinoma after chemoradiotherapy. METHODS: A systematic search was performed in PubMed and EMBASE (1990–2020). The crude data and effect estimates were extracted for each imaging variable. The level of evidence of each variable was assessed and pooled risk ratios (RRs) were calculated. RESULTS: Twenty‐two articles were included in this review, 17 on computed tomography (CT) and 5 on magnetic resonance imaging (MRI) variables. We found strong evidence for the prognostic value of tumor volume at various cut‐off points (pooled RRs ranging from 2.09 to 3.03). Anterior commissure involvement (pooled RR 2.19), posterior commissure involvement (pooled RR 2.44), subglottic extension (pooled RR 2.25), and arytenoid cartilage extension (pooled RR 2.10) were also strong prognostic factors. CONCLUSION: Pretreatment tumor volume and involvement of several subsites are prognostic factors for recurrent laryngeal or hypopharyngeal carcinoma after chemoradiotherapy. John Wiley & Sons, Inc. 2021-04-02 2021-07 /pmc/articles/PMC8252607/ /pubmed/33797818 http://dx.doi.org/10.1002/hed.26698 Text en © 2021 The Authors. Head & Neck published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Clinical Reviews
Smits, Hilde J. G.
Assili, Sanam
Kauw, Frans
Philippens, Marielle E. P.
de Bree, Remco
Dankbaar, Jan W.
Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title_full Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title_fullStr Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title_full_unstemmed Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title_short Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: A systematic review and meta‐analysis
title_sort prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy: a systematic review and meta‐analysis
topic Clinical Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252607/
https://www.ncbi.nlm.nih.gov/pubmed/33797818
http://dx.doi.org/10.1002/hed.26698
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