TRIM28 variants and Wilms' tumour predisposition

TRIM28 was recently identified as a Wilms' tumour (WT) predisposition gene, with germline pathogenic variants identified in around 1% of isolated and 8% of familial WT cases. TRIM28 variants are associated with epithelial WT, but the presence of other tumour components or anaplasia does not exc...

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Detalles Bibliográficos
Autores principales: Hol, Janna A, Diets, Illja J, de Krijger, Ronald R, van den Heuvel‐Eibrink, Marry M, Jongmans, Marjolijn CJ, Kuiper, Roland P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Invited Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252630/
https://www.ncbi.nlm.nih.gov/pubmed/33565090
http://dx.doi.org/10.1002/path.5639

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