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The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
BACKGROUND: In urban environments, some of the most common control tools used against the mosquito disease vector Aedes aegypti are pyrethroid insecticides applied as aerosols, fogs or residual sprays. Their efficacy is compromised by patchy deployment, aging residues, and the evolution and invasion...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252650/ https://www.ncbi.nlm.nih.gov/pubmed/33818874 http://dx.doi.org/10.1002/ps.6398 |
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author | Rigby, Lisa M Johnson, Brian J Peatey, Christopher L Beebe, Nigel W Devine, Gregor J |
author_facet | Rigby, Lisa M Johnson, Brian J Peatey, Christopher L Beebe, Nigel W Devine, Gregor J |
author_sort | Rigby, Lisa M |
collection | PubMed |
description | BACKGROUND: In urban environments, some of the most common control tools used against the mosquito disease vector Aedes aegypti are pyrethroid insecticides applied as aerosols, fogs or residual sprays. Their efficacy is compromised by patchy deployment, aging residues, and the evolution and invasion of pyrethroid‐resistant mosquitoes. A large proportion of mosquitoes in a given environment will therefore receive sublethal doses of insecticide. The potential impact of this sublethal exposure on the behaviour and biology of Ae. aegypti carrying commonly reported resistance alleles is poorly documented. RESULTS: In susceptible insects, sublethal exposure to permethrin resulted in reductions in egg viability (13.9%), blood avidity (16.7%) and male mating success (28.3%). It caused a 70% decrease in the lifespan of exposed susceptible females and a 66% decrease in the insecticide‐resistant females from the parental strain. Exposure to the same dose of insecticide in the presence of the isolated kdr genotype resulted in a smaller impact on female longevity (a 58% decrease) but a 26% increase in eggs per female and a 37% increase in male mating success. Sublethal permethrin exposure reduced host‐location success by 20–30% in all strains. CONCLUSION: The detrimental effects of exposure on susceptible insects were expected, but resistant insects demonstrated a less predictable range of responses, including negative effects on longevity and host‐location but increases in fecundity and mating competitiveness. Overall, sublethal insecticide exposure is expected to increase the competitiveness of resistant phenotypes, acting as a selection pressure for the evolution of permethrin resistance. © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. |
format | Online Article Text |
id | pubmed-8252650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82526502021-07-12 The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti Rigby, Lisa M Johnson, Brian J Peatey, Christopher L Beebe, Nigel W Devine, Gregor J Pest Manag Sci Research Articles BACKGROUND: In urban environments, some of the most common control tools used against the mosquito disease vector Aedes aegypti are pyrethroid insecticides applied as aerosols, fogs or residual sprays. Their efficacy is compromised by patchy deployment, aging residues, and the evolution and invasion of pyrethroid‐resistant mosquitoes. A large proportion of mosquitoes in a given environment will therefore receive sublethal doses of insecticide. The potential impact of this sublethal exposure on the behaviour and biology of Ae. aegypti carrying commonly reported resistance alleles is poorly documented. RESULTS: In susceptible insects, sublethal exposure to permethrin resulted in reductions in egg viability (13.9%), blood avidity (16.7%) and male mating success (28.3%). It caused a 70% decrease in the lifespan of exposed susceptible females and a 66% decrease in the insecticide‐resistant females from the parental strain. Exposure to the same dose of insecticide in the presence of the isolated kdr genotype resulted in a smaller impact on female longevity (a 58% decrease) but a 26% increase in eggs per female and a 37% increase in male mating success. Sublethal permethrin exposure reduced host‐location success by 20–30% in all strains. CONCLUSION: The detrimental effects of exposure on susceptible insects were expected, but resistant insects demonstrated a less predictable range of responses, including negative effects on longevity and host‐location but increases in fecundity and mating competitiveness. Overall, sublethal insecticide exposure is expected to increase the competitiveness of resistant phenotypes, acting as a selection pressure for the evolution of permethrin resistance. © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. John Wiley & Sons, Ltd. 2021-05-06 2021-07 /pmc/articles/PMC8252650/ /pubmed/33818874 http://dx.doi.org/10.1002/ps.6398 Text en © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Articles Rigby, Lisa M Johnson, Brian J Peatey, Christopher L Beebe, Nigel W Devine, Gregor J The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti |
title | The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
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title_full | The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
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title_fullStr | The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
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title_full_unstemmed | The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
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title_short | The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti
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title_sort | impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector aedes aegypti |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252650/ https://www.ncbi.nlm.nih.gov/pubmed/33818874 http://dx.doi.org/10.1002/ps.6398 |
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