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Visual comprehension and orientation into the COVID-19 CIDO ontology

The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontology of standardized COVID terms. The Coronavirus Infectious Disease Ontology (CIDO) is the largest among several COVID ontologies, and it keeps growing, but it is still a medium size...

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Autores principales: Zheng, Ling, Perl, Yehoshua, He, Yongqun, Ochs, Christopher, Geller, James, Liu, Hao, Keloth, Vipina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252699/
https://www.ncbi.nlm.nih.gov/pubmed/34224898
http://dx.doi.org/10.1016/j.jbi.2021.103861
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author Zheng, Ling
Perl, Yehoshua
He, Yongqun
Ochs, Christopher
Geller, James
Liu, Hao
Keloth, Vipina K.
author_facet Zheng, Ling
Perl, Yehoshua
He, Yongqun
Ochs, Christopher
Geller, James
Liu, Hao
Keloth, Vipina K.
author_sort Zheng, Ling
collection PubMed
description The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontology of standardized COVID terms. The Coronavirus Infectious Disease Ontology (CIDO) is the largest among several COVID ontologies, and it keeps growing, but it is still a medium sized ontology. Sophisticated CIDO users, who need more than searching for a specific concept, require orientation and comprehension of CIDO. In previous research, we designed a summarization network called “partial-area taxonomy” to support comprehension of ontologies. The partial-area taxonomy for CIDO is of smaller magnitude than CIDO, but is still too large for comprehension. We present here the “weighted aggregate taxonomy” of CIDO, designed to provide compact views at various granularities of our partial-area taxonomy (and the CIDO ontology). Such a compact view provides a “big picture” of the content of an ontology. In previous work, in the visualization patterns used for partial-area taxonomies, the nodes were arranged in levels according to the numbers of relationships of their concepts. Applying this visualization pattern to CIDO's weighted aggregate taxonomy resulted in an overly long and narrow layout that does not support orientation and comprehension since the names of nodes are barely readable. Thus, we introduce in this paper an innovative visualization of the weighted aggregate taxonomy for better orientation and comprehension of CIDO (and other ontologies). A measure for the efficiency of a layout is introduced and is used to demonstrate the advantage of the new layout over the previous one. With this new visualization, the user can “see the forest for the trees” of the ontology. Benefits of this visualization in highlighting insights into CIDO’s content are provided. Generality of the new layout is demonstrated.
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spelling pubmed-82526992021-07-02 Visual comprehension and orientation into the COVID-19 CIDO ontology Zheng, Ling Perl, Yehoshua He, Yongqun Ochs, Christopher Geller, James Liu, Hao Keloth, Vipina K. J Biomed Inform Original Research The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontology of standardized COVID terms. The Coronavirus Infectious Disease Ontology (CIDO) is the largest among several COVID ontologies, and it keeps growing, but it is still a medium sized ontology. Sophisticated CIDO users, who need more than searching for a specific concept, require orientation and comprehension of CIDO. In previous research, we designed a summarization network called “partial-area taxonomy” to support comprehension of ontologies. The partial-area taxonomy for CIDO is of smaller magnitude than CIDO, but is still too large for comprehension. We present here the “weighted aggregate taxonomy” of CIDO, designed to provide compact views at various granularities of our partial-area taxonomy (and the CIDO ontology). Such a compact view provides a “big picture” of the content of an ontology. In previous work, in the visualization patterns used for partial-area taxonomies, the nodes were arranged in levels according to the numbers of relationships of their concepts. Applying this visualization pattern to CIDO's weighted aggregate taxonomy resulted in an overly long and narrow layout that does not support orientation and comprehension since the names of nodes are barely readable. Thus, we introduce in this paper an innovative visualization of the weighted aggregate taxonomy for better orientation and comprehension of CIDO (and other ontologies). A measure for the efficiency of a layout is introduced and is used to demonstrate the advantage of the new layout over the previous one. With this new visualization, the user can “see the forest for the trees” of the ontology. Benefits of this visualization in highlighting insights into CIDO’s content are provided. Generality of the new layout is demonstrated. Elsevier Inc. 2021-08 2021-07-02 /pmc/articles/PMC8252699/ /pubmed/34224898 http://dx.doi.org/10.1016/j.jbi.2021.103861 Text en © 2021 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Research
Zheng, Ling
Perl, Yehoshua
He, Yongqun
Ochs, Christopher
Geller, James
Liu, Hao
Keloth, Vipina K.
Visual comprehension and orientation into the COVID-19 CIDO ontology
title Visual comprehension and orientation into the COVID-19 CIDO ontology
title_full Visual comprehension and orientation into the COVID-19 CIDO ontology
title_fullStr Visual comprehension and orientation into the COVID-19 CIDO ontology
title_full_unstemmed Visual comprehension and orientation into the COVID-19 CIDO ontology
title_short Visual comprehension and orientation into the COVID-19 CIDO ontology
title_sort visual comprehension and orientation into the covid-19 cido ontology
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252699/
https://www.ncbi.nlm.nih.gov/pubmed/34224898
http://dx.doi.org/10.1016/j.jbi.2021.103861
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