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(2‐Ethylhexyl)sodium: A Hexane‐Soluble Reagent for Br/Na‐Exchanges and Directed Metalations in Continuous Flow

We report the on‐demand generation of hexane‐soluble (2‐ethylhexyl)sodium (1) from 3‐(chloromethyl)heptane (2) using a sodium‐packed‐bed reactor under continuous flow conditions. Thus, the resulting solution of 1 is free of elemental sodium and therefore suited for a range of synthetic applications....

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Detalles Bibliográficos
Autores principales:	Harenberg, Johannes H., Weidmann, Niels, Wiegand, Alexander J., Hoefer, Carla A., Annapureddy, Rajasekar Reddy, Knochel, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252725/ https://www.ncbi.nlm.nih.gov/pubmed/33826212 http://dx.doi.org/10.1002/anie.202103031

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