Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination

Rhodium‐electrocatalyzed arene C−H oxygenation by weakly O‐coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C−H functionalization. Detailed mechanis...

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Autores principales: Tan, Xuefeng, Massignan, Leonardo, Hou, Xiaoyan, Frey, Johanna, Oliveira, João C. A., Hussain, Masoom Nasiha, Ackermann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252749/
https://www.ncbi.nlm.nih.gov/pubmed/33651910
http://dx.doi.org/10.1002/anie.202017359
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author Tan, Xuefeng
Massignan, Leonardo
Hou, Xiaoyan
Frey, Johanna
Oliveira, João C. A.
Hussain, Masoom Nasiha
Ackermann, Lutz
author_facet Tan, Xuefeng
Massignan, Leonardo
Hou, Xiaoyan
Frey, Johanna
Oliveira, João C. A.
Hussain, Masoom Nasiha
Ackermann, Lutz
author_sort Tan, Xuefeng
collection PubMed
description Rhodium‐electrocatalyzed arene C−H oxygenation by weakly O‐coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C−H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation‐induced C−H activation by a bimetallic rhodium catalysis manifold.
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spelling pubmed-82527492021-07-12 Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination Tan, Xuefeng Massignan, Leonardo Hou, Xiaoyan Frey, Johanna Oliveira, João C. A. Hussain, Masoom Nasiha Ackermann, Lutz Angew Chem Int Ed Engl Research Articles Rhodium‐electrocatalyzed arene C−H oxygenation by weakly O‐coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C−H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation‐induced C−H activation by a bimetallic rhodium catalysis manifold. John Wiley and Sons Inc. 2021-05-07 2021-06-07 /pmc/articles/PMC8252749/ /pubmed/33651910 http://dx.doi.org/10.1002/anie.202017359 Text en © 2021 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Tan, Xuefeng
Massignan, Leonardo
Hou, Xiaoyan
Frey, Johanna
Oliveira, João C. A.
Hussain, Masoom Nasiha
Ackermann, Lutz
Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title_full Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title_fullStr Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title_full_unstemmed Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title_short Rhoda‐Electrocatalyzed Bimetallic C−H Oxygenation by Weak O‐Coordination
title_sort rhoda‐electrocatalyzed bimetallic c−h oxygenation by weak o‐coordination
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252749/
https://www.ncbi.nlm.nih.gov/pubmed/33651910
http://dx.doi.org/10.1002/anie.202017359
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