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Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite
The biogenic formation of hemozoin crystals, a crucial process in heme detoxification by the malaria parasite, is reviewed as an antimalarial drug target. We first focus on the in‐vivo formation of hemozoin. A model is presented, based on native‐contrast 3D imaging obtained by X‐ray and electron mic...
Autores principales: | Kapishnikov, Sergey, Hempelmann, Ernst, Elbaum, Michael, Als‐Nielsen, Jens, Leiserowitz, Leslie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252759/ https://www.ncbi.nlm.nih.gov/pubmed/33523575 http://dx.doi.org/10.1002/cmdc.202000895 |
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