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Data integration for the numerical simulation of cardiac electrophysiology

The increasing availability of extensive and accurate clinical data is rapidly shaping cardiovascular care by improving the understanding of physiological and pathological mechanisms of the cardiovascular system and opening new frontiers in designing therapies and interventions. In this direction, m...

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Detalles Bibliográficos
Autores principales: Pagani, Stefano, Dede’, Luca, Manzoni, Andrea, Quarteroni, Alfio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252775/
https://www.ncbi.nlm.nih.gov/pubmed/33594761
http://dx.doi.org/10.1111/pace.14198
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author Pagani, Stefano
Dede’, Luca
Manzoni, Andrea
Quarteroni, Alfio
author_facet Pagani, Stefano
Dede’, Luca
Manzoni, Andrea
Quarteroni, Alfio
author_sort Pagani, Stefano
collection PubMed
description The increasing availability of extensive and accurate clinical data is rapidly shaping cardiovascular care by improving the understanding of physiological and pathological mechanisms of the cardiovascular system and opening new frontiers in designing therapies and interventions. In this direction, mathematical and numerical models provide a complementary relevant tool, able not only to reproduce patient‐specific clinical indicators but also to predict and explore unseen scenarios. With this goal, clinical data are processed and provided as inputs to the mathematical model, which quantitatively describes the physical processes that occur in the cardiac tissue. In this paper, the process of integration of clinical data and mathematical models is discussed. Some challenges and contributions in the field of cardiac electrophysiology are reported.
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spelling pubmed-82527752021-07-12 Data integration for the numerical simulation of cardiac electrophysiology Pagani, Stefano Dede’, Luca Manzoni, Andrea Quarteroni, Alfio Pacing Clin Electrophysiol Review The increasing availability of extensive and accurate clinical data is rapidly shaping cardiovascular care by improving the understanding of physiological and pathological mechanisms of the cardiovascular system and opening new frontiers in designing therapies and interventions. In this direction, mathematical and numerical models provide a complementary relevant tool, able not only to reproduce patient‐specific clinical indicators but also to predict and explore unseen scenarios. With this goal, clinical data are processed and provided as inputs to the mathematical model, which quantitatively describes the physical processes that occur in the cardiac tissue. In this paper, the process of integration of clinical data and mathematical models is discussed. Some challenges and contributions in the field of cardiac electrophysiology are reported. John Wiley and Sons Inc. 2021-03-08 2021-04 /pmc/articles/PMC8252775/ /pubmed/33594761 http://dx.doi.org/10.1111/pace.14198 Text en © 2021 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review
Pagani, Stefano
Dede’, Luca
Manzoni, Andrea
Quarteroni, Alfio
Data integration for the numerical simulation of cardiac electrophysiology
title Data integration for the numerical simulation of cardiac electrophysiology
title_full Data integration for the numerical simulation of cardiac electrophysiology
title_fullStr Data integration for the numerical simulation of cardiac electrophysiology
title_full_unstemmed Data integration for the numerical simulation of cardiac electrophysiology
title_short Data integration for the numerical simulation of cardiac electrophysiology
title_sort data integration for the numerical simulation of cardiac electrophysiology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252775/
https://www.ncbi.nlm.nih.gov/pubmed/33594761
http://dx.doi.org/10.1111/pace.14198
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