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Induction of EBV latent membrane protein-2A (LMP2A)-specific T cells and construction of individualized TCR-engineered T cells for EBV-associated malignancies

BACKGROUND: Latent membrane protein-2A (LMP2A)-specific TCR-engineered T cells could be a promising treatment approach to Epstein–Barr virus-associated malignancies. However, previous studies mainly reported LMP2A-reactive TCRs only focusing on specific HLA subtypes and corresponding epitopes, and t...

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Detalles Bibliográficos
Autores principales:	Zhang, Chaoting, Tan, Qin, Li, Shance, Shen, Luyan, Zhang, Jingtao, Liu, Ying, Yang, Wenjun, Lu, Zheming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252876/ https://www.ncbi.nlm.nih.gov/pubmed/34210819 http://dx.doi.org/10.1136/jitc-2021-002516

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