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Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy

Despite several therapeutic advances, patients with multiple myeloma (MM) require additional treatment options since no curative therapy exists yet. In search of a novel therapeutic antibody, we previously applied phage display with myeloma cell screening and developed TP15, a single-chain fragment...

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Detalles Bibliográficos
Autores principales:	Klausz, Katja, Cieker, Michael, Kellner, Christian, Rösner, Thies, Otte, Anna, Krohn, Steffen, Lux, Anja, Nimmerjahn, Falk, Valerius, Thomas, Gramatzki, Martin, Peipp, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252953/ https://www.ncbi.nlm.nih.gov/pubmed/32499243 http://dx.doi.org/10.3324/haematol.2020.251371

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