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Less is More: We are Administering Too Much Protamine in Cardiac Surgery
CONTEXT: Protamine is routinely administered to neutralize the anticlotting effects of heparin, traditionally at a dose of 1 mg for every 100 IU of heparin—a 1:1 ratio protamine sparing effects—but this is based more on experience and practice than literature evidence. The use of Hemostasis Manageme...
Autores principales: | De Simone, Francesco, Nardelli, Pasquale, Licheri, Margherita, Frau, Giovanna, Redaelli, Martina Baiardo, Monaco, Fabrizio, Zangrillo, Alberto, Landoni, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253032/ https://www.ncbi.nlm.nih.gov/pubmed/33884973 http://dx.doi.org/10.4103/aca.ACA_26_19 |
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