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Infiltration by CXCL10 Secreting Macrophages Is Associated With Antitumor Immunity and Response to Therapy in Ovarian Cancer Subtypes

Ovarian carcinomas (OCs) are poorly immunogenic and immune checkpoint inhibitors (ICIs) have offered a modest benefit. In this study, high CD3(+) T-cells and CD163(+) tumor-associated macrophages (TAMs) densities identify a subgroup of immune infiltrated high-grade serous carcinomas (HGSCs) with bet...

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Detalles Bibliográficos
Autores principales:	Ardighieri, Laura, Missale, Francesco, Bugatti, Mattia, Gatta, Luisa Benerini, Pezzali, Irene, Monti, Matilde, Gottardi, Stefano, Zanotti, Laura, Bignotti, Eliana, Ravaggi, Antonella, Tognon, Germana, Odicino, Franco, Calza, Stefano, Missolo-Koussou, Yoann, Ries, Carola Hermine, Helft, Julie, Vermi, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253056/ https://www.ncbi.nlm.nih.gov/pubmed/34220848 http://dx.doi.org/10.3389/fimmu.2021.690201

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