Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer

Androgen receptor (AR) is the principal molecule in prostate cancer (PCa) etiology and therapy. AR re‐activation still remains a major challenge during treatment of castration‐resistant prostate cancer (CRPC) tumors that relapse after castration therapies. Recent reports have indicated the enrichmen...

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Detalles Bibliográficos
Autores principales: Gao, XinTao, Liang, Jiaqian, Wang, LiYang, Zhang, Zhaoyang, Yuan, Penghui, Wang, Jiaxin, Gao, Yanfei, Ma, Fen, Calagua, Carla, Ye, Huihui, Voznesensky, Olga, Wang, Shaogang, Wang, Tao, Liu, Jihong, Chen, Shaoyong, Liu, Xiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253089/
https://www.ncbi.nlm.nih.gov/pubmed/33932081
http://dx.doi.org/10.1002/1878-0261.12968

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