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Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness

Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that TERT binds directly to the TCF binding elements loca...

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Detalles Bibliográficos
Autores principales: Bernabé‐García, Manuel, Martínez‐Balsalobre, Elena, García‐Moreno, Diana, García‐Castillo, Jesús, Revilla‐Nuin, Beatriz, Blanco‐Alcaina, Elena, Mulero, Victoriano, Alcaraz‐Pérez, Francisca, Cayuela, María L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253104/
https://www.ncbi.nlm.nih.gov/pubmed/33713376
http://dx.doi.org/10.1002/1878-0261.12943