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Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy

Background: ICD-11 features Complex Posttraumatic Stress Disorder (CPTSD) as a new diagnosis. To date, very few studies have investigated CPTSD in young patients, and there is a need for evidence on effective treatment. Objective: The present study evaluates the applicability of developmentally adap...

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Autores principales: Eilers, Rebekka, Rimane, Eline, Vogel, Anna, Renneberg, Babette, Steil, Regina, Rosner, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253183/
https://www.ncbi.nlm.nih.gov/pubmed/34262664
http://dx.doi.org/10.1080/20008198.2021.1929024
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author Eilers, Rebekka
Rimane, Eline
Vogel, Anna
Renneberg, Babette
Steil, Regina
Rosner, Rita
author_facet Eilers, Rebekka
Rimane, Eline
Vogel, Anna
Renneberg, Babette
Steil, Regina
Rosner, Rita
author_sort Eilers, Rebekka
collection PubMed
description Background: ICD-11 features Complex Posttraumatic Stress Disorder (CPTSD) as a new diagnosis. To date, very few studies have investigated CPTSD in young patients, and there is a need for evidence on effective treatment. Objective: The present study evaluates the applicability of developmentally adapted cognitive processing therapy (D-CPT) for CPTSD in young patients in a secondary analysis of the treatment condition of a randomized controlled trial (RCT) investigating the efficacy of D-CPT. Methods: The D-CPT treatment group in the original study included 44 patients (14–21 years) with DSM-IV PTSD after childhood abuse. We used the ICD-11 algorithm to divide the sample into a probable CPTSD and a non-CPTSD group. We performed multilevel models for interviewer-rated and self-rated PTSD symptoms with fixed effects of group (CPTSD, non-CPTSD) and time (up to 12 months follow-up) and their interaction. Treatment response rates for both groups were calculated. Results: Nineteen (43.2%) patients fulfilled criteria for probable ICD-11 CPTSD while 25 (56.8%) did not. Both CPTSD and non-CPTSD groups showed symptom reduction over time. The CPTSD group reported higher symptom severity before and after treatment. Linear improvement and treatment response rates were similar for both groups. D-CPT reduced symptoms of disturbances in self-regulation in both groups. Discussion: Both, patients with and without probable ICD-11 CPTSD seemed to benefit from D-CPT and the treatment also reduced disturbances in self-regulation. Conclusion: This study presents initial evidence of the applicability of D-CPT in clinical practice for young patients with CPTSD. It remains debatable whether CPTSD implies different treatment needs as opposed to PTSD.
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spelling pubmed-82531832021-07-13 Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy Eilers, Rebekka Rimane, Eline Vogel, Anna Renneberg, Babette Steil, Regina Rosner, Rita Eur J Psychotraumatol Clinical Research Article Background: ICD-11 features Complex Posttraumatic Stress Disorder (CPTSD) as a new diagnosis. To date, very few studies have investigated CPTSD in young patients, and there is a need for evidence on effective treatment. Objective: The present study evaluates the applicability of developmentally adapted cognitive processing therapy (D-CPT) for CPTSD in young patients in a secondary analysis of the treatment condition of a randomized controlled trial (RCT) investigating the efficacy of D-CPT. Methods: The D-CPT treatment group in the original study included 44 patients (14–21 years) with DSM-IV PTSD after childhood abuse. We used the ICD-11 algorithm to divide the sample into a probable CPTSD and a non-CPTSD group. We performed multilevel models for interviewer-rated and self-rated PTSD symptoms with fixed effects of group (CPTSD, non-CPTSD) and time (up to 12 months follow-up) and their interaction. Treatment response rates for both groups were calculated. Results: Nineteen (43.2%) patients fulfilled criteria for probable ICD-11 CPTSD while 25 (56.8%) did not. Both CPTSD and non-CPTSD groups showed symptom reduction over time. The CPTSD group reported higher symptom severity before and after treatment. Linear improvement and treatment response rates were similar for both groups. D-CPT reduced symptoms of disturbances in self-regulation in both groups. Discussion: Both, patients with and without probable ICD-11 CPTSD seemed to benefit from D-CPT and the treatment also reduced disturbances in self-regulation. Conclusion: This study presents initial evidence of the applicability of D-CPT in clinical practice for young patients with CPTSD. It remains debatable whether CPTSD implies different treatment needs as opposed to PTSD. Taylor & Francis 2021-06-30 /pmc/articles/PMC8253183/ /pubmed/34262664 http://dx.doi.org/10.1080/20008198.2021.1929024 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research Article
Eilers, Rebekka
Rimane, Eline
Vogel, Anna
Renneberg, Babette
Steil, Regina
Rosner, Rita
Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title_full Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title_fullStr Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title_full_unstemmed Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title_short Response of young patients with probable ICD-11 complex PTSD to treatment with developmentally adapted cognitive processing therapy
title_sort response of young patients with probable icd-11 complex ptsd to treatment with developmentally adapted cognitive processing therapy
topic Clinical Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253183/
https://www.ncbi.nlm.nih.gov/pubmed/34262664
http://dx.doi.org/10.1080/20008198.2021.1929024
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