Clonal evidence for the development of neuroblastoma with extensive copy‐neutral loss of heterozygosity arising in a mature teratoma

Mature teratomas are usually benign tumors that rarely undergo malignant transformation. We report an advanced neuroblastoma arising in a mature teratoma of the ovary. Whole‐exome sequencing identified extensive copy‐neutral loss of heterozygosity (LOH) in both neuroblastoma and teratoma elements, s...

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Detalles Bibliográficos
Autores principales: Ono, Rintaro, Ueno, Hiroo, Yoshida, Kenichi, Takahashi, Satoko, Yoshihara, Hiroki, Nozaki, Taiki, Suzuki, Koyu, Nakazawa, Atsuko, Saiki, Ryunosuke, Seki, Masafumi, Takita, Junko, Ogawa, Seishi, Manabe, Atsushi, Hasegawa, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253283/
https://www.ncbi.nlm.nih.gov/pubmed/33934450
http://dx.doi.org/10.1111/cas.14931

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