Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

Handgrip strength is a widely used measure of muscle strength and a predictor of a range of morbidities including cardiovascular diseases and all-cause mortality. Previous genome-wide association studies of handgrip strength have focused on common variants primarily in persons of European descent. W...

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Detalles Bibliográficos
Autores principales: Sarnowski, Chloé, Chen, Han, Biggs, Mary L., Wassertheil-Smoller, Sylvia, Bressler, Jan, Irvin, Marguerite R., Ryan, Kathleen A., Karasik, David, Arnett, Donna K., Cupples, L. Adrienne, Fardo, David W., Gogarten, Stephanie M., Heavner, Benjamin D., Jain, Deepti, Kang, Hyun Min, Kooperberg, Charles, Mainous, Arch G., Mitchell, Braxton D., Morrison, Alanna C., O’Connell, Jeffrey R., Psaty, Bruce M., Rice, Kenneth, Smith, Albert V., Vasan, Ramachandran S., Windham, B. Gwen, Kiel, Douglas P., Murabito, Joanne M., Lunetta, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253404/
https://www.ncbi.nlm.nih.gov/pubmed/34214102
http://dx.doi.org/10.1371/journal.pone.0253611

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