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Simultaneous Quantification of the Concentration and Carbon Isotopologue Distribution of Polar Metabolites in a Single Analysis by Gas Chromatography and Mass Spectrometry

[Image: see text] (13)C-isotope tracing is a frequently employed approach to study metabolic pathway activity. When combined with the subsequent quantification of absolute metabolite concentrations, this enables detailed characterization of the metabolome in biological specimens and facilitates comp...

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Detalles Bibliográficos
Autores principales: Evers, Bernard, Gerding, Albert, Boer, Theo, Heiner-Fokkema, M. Rebecca, Jalving, Mathilde, Wahl, S. Aljoscha, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253487/
https://www.ncbi.nlm.nih.gov/pubmed/34060804
http://dx.doi.org/10.1021/acs.analchem.1c01040

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