SARS-CoV-2 nucleic acid shedding is variable for every person

INTRODUCTION: Considering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODS: Between March and June 2020, the sequential results of 29 healthcare workers’ were monitored using RT-qPCR. RESULTS: More than 50% of the...

Descripción completa

Detalles Bibliográficos
Autores principales: de Lima-Morales, Daiana, Wink, Priscila Lamb, Volpato, Fabiana Caroline Zempulski, Camargo, Joíza Lins, de-Paris, Fernanda, Barth, Afonso Luís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253572/
https://www.ncbi.nlm.nih.gov/pubmed/34231777
http://dx.doi.org/10.1590/0037-8682-0162-2021
_version_ 1783717539859136512
author de Lima-Morales, Daiana
Wink, Priscila Lamb
Volpato, Fabiana Caroline Zempulski
Camargo, Joíza Lins
de-Paris, Fernanda
Barth, Afonso Luís
author_facet de Lima-Morales, Daiana
Wink, Priscila Lamb
Volpato, Fabiana Caroline Zempulski
Camargo, Joíza Lins
de-Paris, Fernanda
Barth, Afonso Luís
author_sort de Lima-Morales, Daiana
collection PubMed
description INTRODUCTION: Considering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODS: Between March and June 2020, the sequential results of 29 healthcare workers’ were monitored using RT-qPCR. RESULTS: More than 50% of the individuals remained RT-qPCR positive after 14 days. Furthermore, this is the first study to describe positive RT-qPCR for SARS-CoV-2 in a healthcare worker with mild symptoms 95 days after the first positive test. CONCLUSIONS: Sequential RT-qPCR results were heterogeneous, and the viral RNA shedding period is unique for each person.
format Online
Article
Text
id pubmed-8253572
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Sociedade Brasileira de Medicina Tropical - SBMT
record_format MEDLINE/PubMed
spelling pubmed-82535722021-07-13 SARS-CoV-2 nucleic acid shedding is variable for every person de Lima-Morales, Daiana Wink, Priscila Lamb Volpato, Fabiana Caroline Zempulski Camargo, Joíza Lins de-Paris, Fernanda Barth, Afonso Luís Rev Soc Bras Med Trop Short Communication INTRODUCTION: Considering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODS: Between March and June 2020, the sequential results of 29 healthcare workers’ were monitored using RT-qPCR. RESULTS: More than 50% of the individuals remained RT-qPCR positive after 14 days. Furthermore, this is the first study to describe positive RT-qPCR for SARS-CoV-2 in a healthcare worker with mild symptoms 95 days after the first positive test. CONCLUSIONS: Sequential RT-qPCR results were heterogeneous, and the viral RNA shedding period is unique for each person. Sociedade Brasileira de Medicina Tropical - SBMT 2021-07-02 /pmc/articles/PMC8253572/ /pubmed/34231777 http://dx.doi.org/10.1590/0037-8682-0162-2021 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
de Lima-Morales, Daiana
Wink, Priscila Lamb
Volpato, Fabiana Caroline Zempulski
Camargo, Joíza Lins
de-Paris, Fernanda
Barth, Afonso Luís
SARS-CoV-2 nucleic acid shedding is variable for every person
title SARS-CoV-2 nucleic acid shedding is variable for every person
title_full SARS-CoV-2 nucleic acid shedding is variable for every person
title_fullStr SARS-CoV-2 nucleic acid shedding is variable for every person
title_full_unstemmed SARS-CoV-2 nucleic acid shedding is variable for every person
title_short SARS-CoV-2 nucleic acid shedding is variable for every person
title_sort sars-cov-2 nucleic acid shedding is variable for every person
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253572/
https://www.ncbi.nlm.nih.gov/pubmed/34231777
http://dx.doi.org/10.1590/0037-8682-0162-2021
work_keys_str_mv AT delimamoralesdaiana sarscov2nucleicacidsheddingisvariableforeveryperson
AT winkpriscilalamb sarscov2nucleicacidsheddingisvariableforeveryperson
AT volpatofabianacarolinezempulski sarscov2nucleicacidsheddingisvariableforeveryperson
AT camargojoizalins sarscov2nucleicacidsheddingisvariableforeveryperson
AT deparisfernanda sarscov2nucleicacidsheddingisvariableforeveryperson
AT barthafonsoluis sarscov2nucleicacidsheddingisvariableforeveryperson

Ejemplares similares