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Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil

INTRODUCTION: Leptospirosis and brucellosis cause immunosuppression that worsens the clinical condition of people living with HIV/AIDS (PLWHA). We investigated the serological profile and risk factors of PLWHA. METHODS: Serum samples (n=238) were researched for Brucella spp. antibodies using Rose Be...

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Autores principales: Brito, Flavio Gonçalves, Menozzi, Benedito Donizete, Mantovan, Karine Bott, Barbosa, Alexandre Naime, Victória, Cassiano, Langoni, Helio, da Silva, Rodrigo Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253574/
https://www.ncbi.nlm.nih.gov/pubmed/34231771
http://dx.doi.org/10.1590/0037-8682-0076-2021
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author Brito, Flavio Gonçalves
Menozzi, Benedito Donizete
Mantovan, Karine Bott
Barbosa, Alexandre Naime
Victória, Cassiano
Langoni, Helio
da Silva, Rodrigo Costa
author_facet Brito, Flavio Gonçalves
Menozzi, Benedito Donizete
Mantovan, Karine Bott
Barbosa, Alexandre Naime
Victória, Cassiano
Langoni, Helio
da Silva, Rodrigo Costa
author_sort Brito, Flavio Gonçalves
collection PubMed
description INTRODUCTION: Leptospirosis and brucellosis cause immunosuppression that worsens the clinical condition of people living with HIV/AIDS (PLWHA). We investigated the serological profile and risk factors of PLWHA. METHODS: Serum samples (n=238) were researched for Brucella spp. antibodies using Rose Bengal and tube agglutination tests and Leptospira spp. antibodies using the microscopic agglutination test. RESULTS: All samples were negative for Brucella spp. For leptospirosis, four samples (1.69%) were positive, and Andamana was the prevalent serovar. CONCLUSIONS: Low or no detection of these zoonoses does not reduce their importance in PLWHA. Vigilant, educational, and preventive measures should be adopted.
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spelling pubmed-82535742021-07-13 Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil Brito, Flavio Gonçalves Menozzi, Benedito Donizete Mantovan, Karine Bott Barbosa, Alexandre Naime Victória, Cassiano Langoni, Helio da Silva, Rodrigo Costa Rev Soc Bras Med Trop Short Communication INTRODUCTION: Leptospirosis and brucellosis cause immunosuppression that worsens the clinical condition of people living with HIV/AIDS (PLWHA). We investigated the serological profile and risk factors of PLWHA. METHODS: Serum samples (n=238) were researched for Brucella spp. antibodies using Rose Bengal and tube agglutination tests and Leptospira spp. antibodies using the microscopic agglutination test. RESULTS: All samples were negative for Brucella spp. For leptospirosis, four samples (1.69%) were positive, and Andamana was the prevalent serovar. CONCLUSIONS: Low or no detection of these zoonoses does not reduce their importance in PLWHA. Vigilant, educational, and preventive measures should be adopted. Sociedade Brasileira de Medicina Tropical - SBMT 2021-07-02 /pmc/articles/PMC8253574/ /pubmed/34231771 http://dx.doi.org/10.1590/0037-8682-0076-2021 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Brito, Flavio Gonçalves
Menozzi, Benedito Donizete
Mantovan, Karine Bott
Barbosa, Alexandre Naime
Victória, Cassiano
Langoni, Helio
da Silva, Rodrigo Costa
Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title_full Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title_fullStr Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title_full_unstemmed Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title_short Risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern Brazil
title_sort risk factors for leptospirosis and brucellosis in people living with human immunodeficiency virus who attended a referral hospital in southeastern brazil
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253574/
https://www.ncbi.nlm.nih.gov/pubmed/34231771
http://dx.doi.org/10.1590/0037-8682-0076-2021
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