Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Virus-like particles (VLPs) are recognized as an alternative vaccine platform that provide effective protection against various highly pathogenic avian influenza viruses (HPAIVs). Here, we developed multi-clade VLPs expressing two HAs (a chimera of clade 2.3.2.1c and clade 2.3.4.4c HA) within a sing...

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Detalles Bibliográficos
Autores principales: Kang, Yong-Myung, Cho, Hyun-Kyu, Kim, Ju Hun, Lee, Su Jin, Park, Seo-Jeong, Kim, Do-Young, Kim, Seong Yup, Park, Jung-won, Lee, Myoung-Heon, Kim, Min-Chul, Kang, Hyun-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253753/
https://www.ncbi.nlm.nih.gov/pubmed/34215796
http://dx.doi.org/10.1038/s41598-021-93060-8

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