FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

Sialyl-Lewis x (sLe(x), CD15s) is a tetra-saccharide on the surface of leukocytes required for E-selectin-mediated rolling, a prerequisite for leukocytes to migrate out of the blood vessels. Here we show using flow cytometry that sLe(x) expression on basophils and mast cell progenitors depends on fu...

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Detalles Bibliográficos
Autores principales: Puan, Kia Joo, San Luis, Boris, Yusof, Nurhashikin, Kumar, Dilip, Andiappan, Anand Kumar, Lee, Wendy, Cajic, Samanta, Vuckovic, Dragana, Chan, Jing De, Döllner, Tobias, Hou, Han Wei, Jiang, Yunxuan, Tian, Chao, Rapp, Erdmann, Poidinger, Michael, Wang, De Yun, Soranzo, Nicole, Lee, Bernett, Rötzschke, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253766/
https://www.ncbi.nlm.nih.gov/pubmed/34215830
http://dx.doi.org/10.1038/s42003-021-02295-8

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