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Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons
Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also be mediated by the hypothalamic AgRP neurons, which can increase food intake and modify periph...
Autores principales: | Harno, Erika, Sefton, Charlotte, Wray, Jonathan R., Allen, Tiffany-Jayne, Davies, Alison, Coll, Anthony P., White, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253818/ https://www.ncbi.nlm.nih.gov/pubmed/34215821 http://dx.doi.org/10.1038/s41598-021-93378-3 |
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