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Loss of FYCO1 leads to cataract formation
Autophagy is a degradation process of cytoplasmic proteins and organelles trafficked to degradation vesicles known as autophagosomes. The conversion of LC3-I to LC3-II is an essential step of autophagosome formation, and FYCO1 is a LC3-binding protein that mediates autophagosome transport. The p62 p...
Autores principales: | Satoh, Kiyotoshi, Takemura, Yukitoshi, Satoh, Motohiko, Ozaki, Kiyokazu, Kubota, Shunichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253827/ https://www.ncbi.nlm.nih.gov/pubmed/34215815 http://dx.doi.org/10.1038/s41598-021-93110-1 |
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