Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma

Little is known about the transcriptomic plasticity and adaptive mechanisms of circulating tumor cells (CTCs) during hematogeneous dissemination. Here we interrogate the transcriptome of 113 single CTCs from 4 different vascular sites, including hepatic vein (HV), peripheral artery (PA), peripheral...

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Detalles Bibliográficos
Autores principales: Sun, Yun-Fan, Wu, Liang, Liu, Shi-Ping, Jiang, Miao-Miao, Hu, Bo, Zhou, Kai-Qian, Guo, Wei, Xu, Yang, Zhong, Yu, Zhou, Xiao-Rui, Zhang, Ze-Fan, Liu, Geng, Liu, Sheng, Shi, Ying-Hong, Ji, Yuan, Du, Min, Li, Nan-Nan, Li, Gui-Bo, Zhao, Zhi-Kun, Huang, Xiao-Yun, Xu, Li-Qin, Yu, Qi-Chao, Peng, David H., Qiu, Shuang-Jian, Sun, Hui-Chuan, Dean, Michael, Wang, Xiang-Dong, Chung, Wen-Yuan, Dennison, Ashley R., Zhou, Jian, Hou, Yong, Fan, Jia, Yang, Xin-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253833/
https://www.ncbi.nlm.nih.gov/pubmed/34215748
http://dx.doi.org/10.1038/s41467-021-24386-0

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