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Probing mechanobiological role of filamin A in migration and invasion of human U87 glioblastoma cells using submicron soft pillars

Filamin A (FLNa) belongs to an actin-binding protein family in binding and cross-linking actin filaments into a three-dimensional structure. However, little attention has been given to its mechanobiological role in cancer cells. Here, we quantitatively investigated the role of FLNa by analyzing the...

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Detalles Bibliográficos
Autores principales: Ketebo, Abdurazak Aman, Park, Chanyong, Kim, Jaewon, Jun, Myeongjun, Park, Sungsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253861/
https://www.ncbi.nlm.nih.gov/pubmed/34213679
http://dx.doi.org/10.1186/s40580-021-00267-6