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Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report
BACKGROUND: Calcium pyrophosphate dihydrate (CPPD) disease, also known as pyrophosphate arthropathy or pseudogout, is defined as CPPD deposition within the articular cartilage. It was first described in 1962. The representative locations where CPPD disease occurs include the most common knee joint,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253935/ https://www.ncbi.nlm.nih.gov/pubmed/34234447 http://dx.doi.org/10.2147/JMDH.S316738 |
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author | Lo, Po-Cheng Yue, Chung-Tai Kung, Woon-Man |
author_facet | Lo, Po-Cheng Yue, Chung-Tai Kung, Woon-Man |
author_sort | Lo, Po-Cheng |
collection | PubMed |
description | BACKGROUND: Calcium pyrophosphate dihydrate (CPPD) disease, also known as pyrophosphate arthropathy or pseudogout, is defined as CPPD deposition within the articular cartilage. It was first described in 1962. The representative locations where CPPD disease occurs include the most common knee joint, followed by the wrist joint. Joint swelling and pain are the most common clinical presentations, and the typical differential diagnosis is degenerative arthritis. Microscopically, the specimen demonstrates numerous positively birefringent rhomboid shaped crystals when examined under polarized light. CASE REPORT: We present a 70-year-old female with right painful sciatica accompanied by coexisting affected limb soreness and clumsiness. Her final diagnosis was unusual lumbar extradural tumoral pseudogout that was worth noticing. Tumoral CPPD deposition was excised after laminectomy. Subsequently, her symptoms were abated postoperatively without a need for more analgesics. Her neurological function was properly recovered. CONCLUSION: This is a rare report to proffer pseudogout in an unfamiliar lumbar extradural location, which is an unexpected diagnosis. Making a precise tentative diagnosis for the ongoing disease entity might be difficult for the clinicians because the clinical manifestations of this pathology are similar to those of other common degenerative lumbar spinal diseases. |
format | Online Article Text |
id | pubmed-8253935 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-82539352021-07-06 Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report Lo, Po-Cheng Yue, Chung-Tai Kung, Woon-Man J Multidiscip Healthc Case Report BACKGROUND: Calcium pyrophosphate dihydrate (CPPD) disease, also known as pyrophosphate arthropathy or pseudogout, is defined as CPPD deposition within the articular cartilage. It was first described in 1962. The representative locations where CPPD disease occurs include the most common knee joint, followed by the wrist joint. Joint swelling and pain are the most common clinical presentations, and the typical differential diagnosis is degenerative arthritis. Microscopically, the specimen demonstrates numerous positively birefringent rhomboid shaped crystals when examined under polarized light. CASE REPORT: We present a 70-year-old female with right painful sciatica accompanied by coexisting affected limb soreness and clumsiness. Her final diagnosis was unusual lumbar extradural tumoral pseudogout that was worth noticing. Tumoral CPPD deposition was excised after laminectomy. Subsequently, her symptoms were abated postoperatively without a need for more analgesics. Her neurological function was properly recovered. CONCLUSION: This is a rare report to proffer pseudogout in an unfamiliar lumbar extradural location, which is an unexpected diagnosis. Making a precise tentative diagnosis for the ongoing disease entity might be difficult for the clinicians because the clinical manifestations of this pathology are similar to those of other common degenerative lumbar spinal diseases. Dove 2021-06-28 /pmc/articles/PMC8253935/ /pubmed/34234447 http://dx.doi.org/10.2147/JMDH.S316738 Text en © 2021 Lo et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Lo, Po-Cheng Yue, Chung-Tai Kung, Woon-Man Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title | Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title_full | Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title_fullStr | Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title_full_unstemmed | Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title_short | Lumbar Extradural Pseudogout Mass Manifesting as Radiculopathy: A Case Report |
title_sort | lumbar extradural pseudogout mass manifesting as radiculopathy: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253935/ https://www.ncbi.nlm.nih.gov/pubmed/34234447 http://dx.doi.org/10.2147/JMDH.S316738 |
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