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Coupling size exclusion chromatography to ultracentrifugation improves detection of exosomal proteins from human plasma by LC-MS

OBJECTIVES: Exosomes are small lipid bilayer vesicles that are defined by their endocytic origin and size range of 30–140 nm. They are constantly produced by different cell types, by both healthy and abnormal cells, and can be isolated from almost all body fluids. Little information exists in isolat...

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Detalles Bibliográficos
Autores principales: Alameldin, Sara, Costina, Victor, Abdel-Baset, Hesham A., Nitschke, Katja, Nuhn, Phillip, Neumaier, Michael, Hedtke, Maren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254000/
https://www.ncbi.nlm.nih.gov/pubmed/34258353
http://dx.doi.org/10.1016/j.plabm.2021.e00241

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