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Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD
PURPOSE: This study aims to define which of the right ventricular myocardial deformation indices best correlates with the classic echocardiographic measurements and indices of right ventricular (RV) dysfunction in patients with stable chronic obstructive pulmonary disease (COPD). PATIENTS AND METHOD...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254030/ https://www.ncbi.nlm.nih.gov/pubmed/34234427 http://dx.doi.org/10.2147/COPD.S290957 |
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author | Masson Silva, João Batista Tannus Silva, Daniela Graner Schuwartz Furtado, Rogério Gomes da Silva Júnior, Cloves Geraldino Araújo, Fabrício Alves Costa, Sandra de Araújo Marra da Madeira Freitas, Elis Rassi, Daniela do Carmo Rabahi, Marcelo Fouad Rassi, Salvador |
author_facet | Masson Silva, João Batista Tannus Silva, Daniela Graner Schuwartz Furtado, Rogério Gomes da Silva Júnior, Cloves Geraldino Araújo, Fabrício Alves Costa, Sandra de Araújo Marra da Madeira Freitas, Elis Rassi, Daniela do Carmo Rabahi, Marcelo Fouad Rassi, Salvador |
author_sort | Masson Silva, João Batista |
collection | PubMed |
description | PURPOSE: This study aims to define which of the right ventricular myocardial deformation indices best correlates with the classic echocardiographic measurements and indices of right ventricular (RV) dysfunction in patients with stable chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS: Ninety-one patients with stable COPD underwent clinical evaluation, spirometry, a 6-minute walk test, and echocardiographic examination. Patients were divided into two groups: “with RV dysfunction” (≥1 classic parameter) and “without RV dysfunction”. We used speckle tracking to estimate myocardial deformation. For all analyses, results were considered significant if p < 0.05. RESULTS: The mean age across all participants was 65 ± 9 years, with 53% (48/91) being male. Patients in the group with RV dysfunction were able to walk shorter distances and had higher estimated right ventricular systolic pressure (RVSP) and mean pulmonary arterial pressure (mPAP). The RV free wall longitudinal strain (RVFWLS) was the only deformation indices that showed a significant correlation with all classic measurements and indices in the diagnosis of RV dysfunction (Wald test, 10.24; p < 0.01; odds ratio, 1.61). In the ROC curve analysis, the absolute value <20% was the lowest cut-off point of this index for detection of RV dysfunction (AUC = 0.93, S: 95.8%, and E: 88%). CONCLUSION: In COPD patients, RVFWLS is the myocardial deformation index that best correlates with classic echocardiographic parameters for the diagnosis of RV dysfunction using <20% as a cut-off point. |
format | Online Article Text |
id | pubmed-8254030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-82540302021-07-06 Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD Masson Silva, João Batista Tannus Silva, Daniela Graner Schuwartz Furtado, Rogério Gomes da Silva Júnior, Cloves Geraldino Araújo, Fabrício Alves Costa, Sandra de Araújo Marra da Madeira Freitas, Elis Rassi, Daniela do Carmo Rabahi, Marcelo Fouad Rassi, Salvador Int J Chron Obstruct Pulmon Dis Original Research PURPOSE: This study aims to define which of the right ventricular myocardial deformation indices best correlates with the classic echocardiographic measurements and indices of right ventricular (RV) dysfunction in patients with stable chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS: Ninety-one patients with stable COPD underwent clinical evaluation, spirometry, a 6-minute walk test, and echocardiographic examination. Patients were divided into two groups: “with RV dysfunction” (≥1 classic parameter) and “without RV dysfunction”. We used speckle tracking to estimate myocardial deformation. For all analyses, results were considered significant if p < 0.05. RESULTS: The mean age across all participants was 65 ± 9 years, with 53% (48/91) being male. Patients in the group with RV dysfunction were able to walk shorter distances and had higher estimated right ventricular systolic pressure (RVSP) and mean pulmonary arterial pressure (mPAP). The RV free wall longitudinal strain (RVFWLS) was the only deformation indices that showed a significant correlation with all classic measurements and indices in the diagnosis of RV dysfunction (Wald test, 10.24; p < 0.01; odds ratio, 1.61). In the ROC curve analysis, the absolute value <20% was the lowest cut-off point of this index for detection of RV dysfunction (AUC = 0.93, S: 95.8%, and E: 88%). CONCLUSION: In COPD patients, RVFWLS is the myocardial deformation index that best correlates with classic echocardiographic parameters for the diagnosis of RV dysfunction using <20% as a cut-off point. Dove 2021-06-28 /pmc/articles/PMC8254030/ /pubmed/34234427 http://dx.doi.org/10.2147/COPD.S290957 Text en © 2021 Masson Silva et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Masson Silva, João Batista Tannus Silva, Daniela Graner Schuwartz Furtado, Rogério Gomes da Silva Júnior, Cloves Geraldino Araújo, Fabrício Alves Costa, Sandra de Araújo Marra da Madeira Freitas, Elis Rassi, Daniela do Carmo Rabahi, Marcelo Fouad Rassi, Salvador Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title | Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title_full | Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title_fullStr | Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title_full_unstemmed | Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title_short | Correlation Between 2D Strain and Classic Echocardiographic Indices in the Diagnosis of Right Ventricular Dysfunction in COPD |
title_sort | correlation between 2d strain and classic echocardiographic indices in the diagnosis of right ventricular dysfunction in copd |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254030/ https://www.ncbi.nlm.nih.gov/pubmed/34234427 http://dx.doi.org/10.2147/COPD.S290957 |
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