Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries

Magnetic Resonance-guided Radiotherapy (MRgRT) allows direct monitoring of treated volumes. The aim of this study was to investigate the feasibility of a new gating strategy consisting in using an isodose as boundary. Forty-four patients treated for thoracic and abdominal lesions using MRgRT were en...

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Autores principales: Votta, Claudio, Cusumano, Davide, Boldrini, Luca, Dinapoli, Nicola, Placidi, Lorenzo, Turco, Gabriele, Antonelli, Marco Valerio, Pollutri, Veronica, Romano, Angela, Indovina, Luca, Valentini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254198/
https://www.ncbi.nlm.nih.gov/pubmed/34258412
http://dx.doi.org/10.1016/j.phro.2021.05.005
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author Votta, Claudio
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Placidi, Lorenzo
Turco, Gabriele
Antonelli, Marco Valerio
Pollutri, Veronica
Romano, Angela
Indovina, Luca
Valentini, Vincenzo
author_facet Votta, Claudio
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Placidi, Lorenzo
Turco, Gabriele
Antonelli, Marco Valerio
Pollutri, Veronica
Romano, Angela
Indovina, Luca
Valentini, Vincenzo
author_sort Votta, Claudio
collection PubMed
description Magnetic Resonance-guided Radiotherapy (MRgRT) allows direct monitoring of treated volumes. The aim of this study was to investigate the feasibility of a new gating strategy consisting in using an isodose as boundary. Forty-four patients treated for thoracic and abdominal lesions using MRgRT were enrolled. The accuracy of the new strategy was compared to the conventional one in terms of area improvement available for gating without compromising target coverage. A mean increase of 24% for lung, 15% for liver and 11% for pancreas was observed, demonstrating how the new method can be useful in challenging situations with low dose conformality.
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spelling pubmed-82541982021-07-12 Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries Votta, Claudio Cusumano, Davide Boldrini, Luca Dinapoli, Nicola Placidi, Lorenzo Turco, Gabriele Antonelli, Marco Valerio Pollutri, Veronica Romano, Angela Indovina, Luca Valentini, Vincenzo Phys Imaging Radiat Oncol Short Communication Magnetic Resonance-guided Radiotherapy (MRgRT) allows direct monitoring of treated volumes. The aim of this study was to investigate the feasibility of a new gating strategy consisting in using an isodose as boundary. Forty-four patients treated for thoracic and abdominal lesions using MRgRT were enrolled. The accuracy of the new strategy was compared to the conventional one in terms of area improvement available for gating without compromising target coverage. A mean increase of 24% for lung, 15% for liver and 11% for pancreas was observed, demonstrating how the new method can be useful in challenging situations with low dose conformality. Elsevier 2021-06-07 /pmc/articles/PMC8254198/ /pubmed/34258412 http://dx.doi.org/10.1016/j.phro.2021.05.005 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Votta, Claudio
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Placidi, Lorenzo
Turco, Gabriele
Antonelli, Marco Valerio
Pollutri, Veronica
Romano, Angela
Indovina, Luca
Valentini, Vincenzo
Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title_full Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title_fullStr Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title_full_unstemmed Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title_short Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
title_sort delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254198/
https://www.ncbi.nlm.nih.gov/pubmed/34258412
http://dx.doi.org/10.1016/j.phro.2021.05.005
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