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Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axis

BACKGROUND: Osteosarcoma (OS) is a common type of bone malignancy that often occurs in children and adolescents. Chemoresistance is a huge barrier to cancer therapy. This study aimed to investigate the role and potential mechanism of circ_0001721 in doxorubicin (DXR) resistance and OS development. M...

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Detalles Bibliográficos
Autores principales:	Guan, Huapeng, Xu, Hao, Chen, Jinshui, Wu, Weishan, Chen, Dongfeng, Chen, Yungang, Sun, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254259/ https://www.ncbi.nlm.nih.gov/pubmed/34215252 http://dx.doi.org/10.1186/s12935-021-02016-5

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