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High-efficiency c-Myc-mediated induction of functional hepatoblasts from the human umbilical cord mesenchymal stem cells

BACKGROUND: Direct reprogramming of human fibroblasts to hepatocyte-like cells was proposed to generate large-scale functional hepatocytes demanded by liver tissue engineering. However, the difficulty in obtaining large quantities of human fibroblasts greatly restricted the extensive implementation...

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Detalles Bibliográficos
Autores principales:	Deng, Jie, Luo, Kai, Xu, Pengchao, Jiang, Qingyuan, Wang, Yuan, Yao, Yunqi, Chen, Xiaolei, Cheng, Fuyi, Xie, Dan, Deng, Hongxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254319/ https://www.ncbi.nlm.nih.gov/pubmed/34215318 http://dx.doi.org/10.1186/s13287-021-02419-1

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