Cargando…

Clinical significance of FBXW7 tumor suppressor gene mutations and expression in human colorectal cancer: a systemic review and meta-analysis

BACKGROUND: Various studies investigating the clinical significance of FBXW7 mutation and/or expression have yielded inconclusive results in colorectal cancer (CRC) patients. Therefore, the present meta-analysis summarizes previous evidence and evaluates the clinical significance, including the prog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shang, Wei, Yan, Chuanwang, Liu, Ran, Chen, Lili, Cheng, Dongdong, Hao, Liang, Yuan, Wenguang, Chen, Jingbo, Yang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254329/ https://www.ncbi.nlm.nih.gov/pubmed/34217244 http://dx.doi.org/10.1186/s12885-021-08535-8

Ejemplares similares

Clinical significance of mucinous component in colorectal adenocarcinoma: a propensity score-matched study
por: Yan, Chuanwang, et al.
Publicado: (2021)

Prognostic Significance of NOTCH1 and FBXW7 Mutations in Pediatric T-ALL
por: Erbilgin, Yucel, et al.
Publicado: (2010)

Comprehensive characterization of FBXW7 mutational and clinicopathological profiles in human colorectal cancers
por: Liu, Yiping, et al.
Publicado: (2023)

FBXW7: a critical tumor suppressor of human cancers
por: Yeh, Chien-Hung, et al.
Publicado: (2018)

Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis
por: Cao, Jun, et al.
Publicado: (2016)

Tumor Suppressor FBXW7 and Its Regulation of DNA Damage Response and Repair
por: Lan, Huiyin, et al.
Publicado: (2021)

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
por: Jiménez-Izquierdo, Rafael, et al.
Publicado: (2023)

Clinical significance of FBXW7 loss of function in human cancers
por: Fan, Jingyi, et al.
Publicado: (2022)

N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil Targeting FBXW7 Tumor Suppressor
por: Fiore, Donatella, et al.
Publicado: (2019)

MicroRNA-92b targets tumor suppressor gene FBXW7 in glioblastoma
por: Grafals-Ruiz, Nilmary, et al.
Publicado: (2023)

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma
por: Korphaisarn, Krittiya, et al.
Publicado: (2017)

Mutational Status of SMAD4 and FBXW7 Affects Clinical Outcome in TP53–Mutated Metastatic Colorectal Cancer
por: Lahoz, Sara, et al.
Publicado: (2022)

FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells
por: Yang, Hui, et al.
Publicado: (2015)

FBXW7 in breast cancer: mechanism of action and therapeutic potential
por: Chen, Siyu, et al.
Publicado: (2023)

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7
por: Wang, Zeran, et al.
Publicado: (2013)

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15
por: Li, Ningning, et al.
Publicado: (2015)

The Role of FBXW7 in Gynecologic Malignancies
por: Di Fiore, Riccardo, et al.
Publicado: (2023)

The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor
por: Xu, Jie, et al.
Publicado: (2017)

MYC is a critical target of FBXW7
por: Sato, Mai, et al.
Publicado: (2014)

A widely used pan-isoform-FBXW7 antibody used in cell cycle studies does not detect FBXW7
por: Ennis, Hannah, et al.
Publicado: (2023)

Role of FBXW7 expression in gastric cancer: Meta‑analysis and bioinformatics analysis
por: Sun, Jing, et al.
Publicado: (2023)

Intratumor Heterogeneity of MYO18A and FBXW7 Variants Impact the Clinical Outcome of Stage III Colorectal Cancer
por: Lin, Peng-Chan, et al.
Publicado: (2020)

Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia
por: Liu, Rong-Bin, et al.
Publicado: (2017)

FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
por: Wei, Wenxia, et al.
Publicado: (2023)

FBXW7 expression is associated with prognosis and chemotherapeutic outcome in Chinese patients with gastric adenocarcinoma
por: Li, Mao-Ran, et al.
Publicado: (2017)

Regulation of BRAF protein stability by a negative feedback loop involving the MEK–ERK pathway but not the FBXW7 tumour suppressor
por: Hernandez, Maria Aguilar, et al.
Publicado: (2016)

Alteration in Expression of miR-32 and FBXW7 Tumor Suppressor in Plasma Samples of Patients with T-cell Acute Lymphoblastic Leukemia
por: Mansouri, Sanaz, et al.
Publicado: (2020)

Loss of CDC4/FBXW7 in Gastric Carinoma
por: Milne, A. N., et al.
Publicado: (2010)

Examination of the expression levels of MACC1, Filamin A and FBXW7 genes in colorectal cancer patients
por: Yesilkaya, Funda, et al.
Publicado: (2019)

FBXW7 attenuates tumor drug resistance and enhances the efficacy of immunotherapy
por: Chen, Shimin, et al.
Publicado: (2023)

Circular RNA circFBXW4 suppresses hepatic fibrosis via targeting the miR-18b-3p/FBXW7 axis
por: Chen, Xin, et al.
Publicado: (2020)

The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia
por: Mansour, Marc R., et al.
Publicado: (2013)

miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7
por: Wang, Bei, et al.
Publicado: (2020)

Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity
por: Izumi, Nanae, et al.
Publicado: (2012)

Regulation of GSK3β-FBXW7-JUNB Axis
por: Pérez-Benavente, Beatriz, et al.
Publicado: (2013)

FBXW7 and the Hallmarks of Cancer: Underlying Mechanisms and Prospective Strategies
por: Shen, Wenyue, et al.
Publicado: (2022)

Recent Insight on Regulations of FBXW7 and Its Role in Immunotherapy
por: Xing, Liangliang, et al.
Publicado: (2022)

FBXW7 Mutations in Patients with Advanced Cancers: Clinical and Molecular Characteristics and Outcomes with mTOR Inhibitors
por: Jardim, Denis L., et al.
Publicado: (2014)

FBXW7 inactivation induces cellular senescence via accumulation of p53
por: Gong, Longyuan, et al.
Publicado: (2022)

MicroRNA-92a promotes non-small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7
por: Ni, Da, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1d7m1dl548h59rllrsrhf8pv5p