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Targeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling
BACKGROUND: Some driver oncogenes are still unknown in non-small-cell lung cancer (NSCLC). DNAJC19, a major component of the translocation machinery of mitochondrial membranes, is a disease-associated protein. Herein, we report the role of DNAJC19 in NSCLC cell growth and metastasis. METHODS: Immuno...
Autores principales: | Zhou, Ji, Peng, Yang, Gao, Ying-chun, Chen, Tai-yu, Li, Peng-cheng, Xu, Ke, Liu, Tao, Ren, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254338/ https://www.ncbi.nlm.nih.gov/pubmed/34217321 http://dx.doi.org/10.1186/s12935-021-02054-z |
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