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Targeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling

BACKGROUND: Some driver oncogenes are still unknown in non-small-cell lung cancer (NSCLC). DNAJC19, a major component of the translocation machinery of mitochondrial membranes, is a disease-associated protein. Herein, we report the role of DNAJC19 in NSCLC cell growth and metastasis. METHODS: Immuno...

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Detalles Bibliográficos
Autores principales: Zhou, Ji, Peng, Yang, Gao, Ying-chun, Chen, Tai-yu, Li, Peng-cheng, Xu, Ke, Liu, Tao, Ren, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254338/
https://www.ncbi.nlm.nih.gov/pubmed/34217321
http://dx.doi.org/10.1186/s12935-021-02054-z

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