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A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
BACKGROUND: During eye lens development the embryonic vasculature regresses leaving the lens without a direct oxygen source. Both embryonically and throughout adult life, the lens contains a decreasing oxygen gradient from the surface to the core that parallels the natural differentiation of immatur...
Autores principales: | Disatham, Joshua, Brennan, Lisa, Chauss, Daniel, Kantorow, Jason, Afzali, Behdad, Kantorow, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254356/ https://www.ncbi.nlm.nih.gov/pubmed/34215186 http://dx.doi.org/10.1186/s12864-021-07795-9 |
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