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PhyliCS: a Python library to explore scCNA data and quantify spatial tumor heterogeneity

BACKGROUND: Tumors are composed by a number of cancer cell subpopulations (subclones), characterized by a distinguishable set of mutations. This phenomenon, known as intra-tumor heterogeneity (ITH), may be studied using Copy Number Aberrations (CNAs). Nowadays ITH can be assessed at the highest poss...

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Detalles Bibliográficos
Autores principales:	Montemurro, Marilisa, Grassi, Elena, Pizzino, Carmelo Gabriele, Bertotti, Andrea, Ficarra, Elisa, Urgese, Gianvito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254361/ https://www.ncbi.nlm.nih.gov/pubmed/34217219 http://dx.doi.org/10.1186/s12859-021-04277-3

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