Synthetic and computational efforts towards the development of peptidomimetics and small-molecule SARS-CoV 3CLpro inhibitors

Severe Acute Respiratory Syndrome (SARS) is a severe febrile respiratory disease caused by the beta genus of human coronavirus, known as SARS-CoV. Last year, 2019-n-CoV (COVID-19) was a global threat for everyone caused by the outbreak of SARS-CoV-2. 3CLpro, chymotrypsin-like protease, is a major cy...

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Detalles Bibliográficos
Autores principales: Paul, Abhik, Sarkar, Arnab, Saha, Sanjukta, Maji, Avik, Janah, Pritha, Kumar Maity, Tapan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254399/
https://www.ncbi.nlm.nih.gov/pubmed/34332853
http://dx.doi.org/10.1016/j.bmc.2021.116301

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