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Inhibition of SIRT1 Limits Self-Renewal and Oncogenesis by Inducing Senescence of Liver Cancer Stem Cells

PURPOSE: Cancer stem cells (CSCs) have been considered involving in tumorigenesis, local recurrence, and therapeutic drug resistance of hepatocellular carcinoma (HCC). To investigate novel and effective methods for targeting hepatic CSCs is crucial for a permanent cure of liver cancer. METHODS: The...

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Detalles Bibliográficos
Autores principales: Wang, Min-Jun, Chen, Jia-Jia, Song, Shao-Hua, Su, Jing, Zhao, Ling-Hao, Liu, Qing-Gui, Yang, Tao, Chen, Zhiwen, Liu, Chang, Fu, Zhi-Ren, Hu, Yi-Ping, Chen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254544/
https://www.ncbi.nlm.nih.gov/pubmed/34235106
http://dx.doi.org/10.2147/JHC.S296234