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Inhibition of SIRT1 Limits Self-Renewal and Oncogenesis by Inducing Senescence of Liver Cancer Stem Cells
PURPOSE: Cancer stem cells (CSCs) have been considered involving in tumorigenesis, local recurrence, and therapeutic drug resistance of hepatocellular carcinoma (HCC). To investigate novel and effective methods for targeting hepatic CSCs is crucial for a permanent cure of liver cancer. METHODS: The...
Autores principales: | Wang, Min-Jun, Chen, Jia-Jia, Song, Shao-Hua, Su, Jing, Zhao, Ling-Hao, Liu, Qing-Gui, Yang, Tao, Chen, Zhiwen, Liu, Chang, Fu, Zhi-Ren, Hu, Yi-Ping, Chen, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254544/ https://www.ncbi.nlm.nih.gov/pubmed/34235106 http://dx.doi.org/10.2147/JHC.S296234 |
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