Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics

Psoriasis is a common chronic inflammatory skin disease associated with several comorbidities and reduced quality of life. In the past decades, highly effective targeted therapies have led to breakthroughs in the management of psoriasis, providing important insights into the pathogenesis. This artic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ben Abdallah, Hakim, Johansen, Claus, Iversen, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254604/
https://www.ncbi.nlm.nih.gov/pubmed/34235053
http://dx.doi.org/10.2147/PTT.S294173
_version_ 1783717762399469568
author Ben Abdallah, Hakim
Johansen, Claus
Iversen, Lars
author_facet Ben Abdallah, Hakim
Johansen, Claus
Iversen, Lars
author_sort Ben Abdallah, Hakim
collection PubMed
description Psoriasis is a common chronic inflammatory skin disease associated with several comorbidities and reduced quality of life. In the past decades, highly effective targeted therapies have led to breakthroughs in the management of psoriasis, providing important insights into the pathogenesis. This article reviews the current concepts of the pathophysiological pathways and the recent progress in antipsoriatic therapeutics, highlighting key targets, signaling pathways and clinical effects in psoriasis.
format Online
Article
Text
id pubmed-8254604
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-82546042021-07-06 Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics Ben Abdallah, Hakim Johansen, Claus Iversen, Lars Psoriasis (Auckl) Review Psoriasis is a common chronic inflammatory skin disease associated with several comorbidities and reduced quality of life. In the past decades, highly effective targeted therapies have led to breakthroughs in the management of psoriasis, providing important insights into the pathogenesis. This article reviews the current concepts of the pathophysiological pathways and the recent progress in antipsoriatic therapeutics, highlighting key targets, signaling pathways and clinical effects in psoriasis. Dove 2021-06-29 /pmc/articles/PMC8254604/ /pubmed/34235053 http://dx.doi.org/10.2147/PTT.S294173 Text en © 2021 Ben Abdallah et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Ben Abdallah, Hakim
Johansen, Claus
Iversen, Lars
Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title_full Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title_fullStr Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title_full_unstemmed Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title_short Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics
title_sort key signaling pathways in psoriasis: recent insights from antipsoriatic therapeutics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254604/
https://www.ncbi.nlm.nih.gov/pubmed/34235053
http://dx.doi.org/10.2147/PTT.S294173
work_keys_str_mv AT benabdallahhakim keysignalingpathwaysinpsoriasisrecentinsightsfromantipsoriatictherapeutics
AT johansenclaus keysignalingpathwaysinpsoriasisrecentinsightsfromantipsoriatictherapeutics
AT iversenlars keysignalingpathwaysinpsoriasisrecentinsightsfromantipsoriatictherapeutics

Ejemplares similares