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Safety and structural integrity of N95/PFF2 respirators decontamination

BACKGROUND: COVID-19 is caused by the SARS-CoV-2 virus, an emerging respiratory pathogen. The work environment represents a high-risk factor for health professionals. Given the scarcity of protective personal equipment due to global demand, decontamination and reuse studies should be carried out. Th...

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Autores principales: Coelho, Wanderson Eduardo Gomes de Souza, Perrechil, Fabiana, Pedreira, Mavilde L.G., Lopes, Juliana Lima, Santos, Maria Valdenice Lopes dos, Gabrieloni, Maria Cristina, Perfeito, João Alessio, Moraes, Mariana Agostini de, Taminato, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254646/
https://www.ncbi.nlm.nih.gov/pubmed/34229034
http://dx.doi.org/10.1016/j.ajic.2021.06.018
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author Coelho, Wanderson Eduardo Gomes de Souza
Perrechil, Fabiana
Pedreira, Mavilde L.G.
Lopes, Juliana Lima
Santos, Maria Valdenice Lopes dos
Gabrieloni, Maria Cristina
Perfeito, João Alessio
Moraes, Mariana Agostini de
Taminato, Monica
author_facet Coelho, Wanderson Eduardo Gomes de Souza
Perrechil, Fabiana
Pedreira, Mavilde L.G.
Lopes, Juliana Lima
Santos, Maria Valdenice Lopes dos
Gabrieloni, Maria Cristina
Perfeito, João Alessio
Moraes, Mariana Agostini de
Taminato, Monica
author_sort Coelho, Wanderson Eduardo Gomes de Souza
collection PubMed
description BACKGROUND: COVID-19 is caused by the SARS-CoV-2 virus, an emerging respiratory pathogen. The work environment represents a high-risk factor for health professionals. Given the scarcity of protective personal equipment due to global demand, decontamination and reuse studies should be carried out. Thus, the aim of this study was to evaluate the safety of a method of decontamination of N95/PFF2 respirators, especially regarding structural integrity. METHODS: N95/PFF2 respirators were subjected to hydrogen peroxide decontamination and analyzed using scanning electron microscopy and thermogravimetric analysis. Seven respirators of the same brand and lot were used, one being a control and the other six subjected to decontamination process. As for the sealing, a qualitative test was applied, in order to identify the changes in the structure that could damage the sealing of respirators. RESULTS: Indicated that the fiber morphology in all layers was not affected by the six decontamination cycles. Also, the thermal stability in the different layers was very similar. Fit testing showed that the respiradors submitted to all cycles of decontamination were approved. CONCLUSIONS: Thus, it is possible to conclude that the hydrogen peroxide decontamination method is effective, since it does not alter the physical properties of the respirators.
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spelling pubmed-82546462021-07-06 Safety and structural integrity of N95/PFF2 respirators decontamination Coelho, Wanderson Eduardo Gomes de Souza Perrechil, Fabiana Pedreira, Mavilde L.G. Lopes, Juliana Lima Santos, Maria Valdenice Lopes dos Gabrieloni, Maria Cristina Perfeito, João Alessio Moraes, Mariana Agostini de Taminato, Monica Am J Infect Control Major Article BACKGROUND: COVID-19 is caused by the SARS-CoV-2 virus, an emerging respiratory pathogen. The work environment represents a high-risk factor for health professionals. Given the scarcity of protective personal equipment due to global demand, decontamination and reuse studies should be carried out. Thus, the aim of this study was to evaluate the safety of a method of decontamination of N95/PFF2 respirators, especially regarding structural integrity. METHODS: N95/PFF2 respirators were subjected to hydrogen peroxide decontamination and analyzed using scanning electron microscopy and thermogravimetric analysis. Seven respirators of the same brand and lot were used, one being a control and the other six subjected to decontamination process. As for the sealing, a qualitative test was applied, in order to identify the changes in the structure that could damage the sealing of respirators. RESULTS: Indicated that the fiber morphology in all layers was not affected by the six decontamination cycles. Also, the thermal stability in the different layers was very similar. Fit testing showed that the respiradors submitted to all cycles of decontamination were approved. CONCLUSIONS: Thus, it is possible to conclude that the hydrogen peroxide decontamination method is effective, since it does not alter the physical properties of the respirators. Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021-10 2021-07-03 /pmc/articles/PMC8254646/ /pubmed/34229034 http://dx.doi.org/10.1016/j.ajic.2021.06.018 Text en © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Major Article
Coelho, Wanderson Eduardo Gomes de Souza
Perrechil, Fabiana
Pedreira, Mavilde L.G.
Lopes, Juliana Lima
Santos, Maria Valdenice Lopes dos
Gabrieloni, Maria Cristina
Perfeito, João Alessio
Moraes, Mariana Agostini de
Taminato, Monica
Safety and structural integrity of N95/PFF2 respirators decontamination
title Safety and structural integrity of N95/PFF2 respirators decontamination
title_full Safety and structural integrity of N95/PFF2 respirators decontamination
title_fullStr Safety and structural integrity of N95/PFF2 respirators decontamination
title_full_unstemmed Safety and structural integrity of N95/PFF2 respirators decontamination
title_short Safety and structural integrity of N95/PFF2 respirators decontamination
title_sort safety and structural integrity of n95/pff2 respirators decontamination
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254646/
https://www.ncbi.nlm.nih.gov/pubmed/34229034
http://dx.doi.org/10.1016/j.ajic.2021.06.018
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