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Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank

AIM: Alcohol‐related problems, including trauma, are a great burden on global health. Alcohol metabolism in the Japanese population is genetically inferior to other races. This study aimed to evaluate the effects of alcohol use among a Japanese severe blunt trauma cohort. METHODS: This retrospective...

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Autores principales: Sasaki, Kazuma, Obinata, Hirofumi, Yokobori, Shoji, Sakamoto, Taigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254651/
https://www.ncbi.nlm.nih.gov/pubmed/34262778
http://dx.doi.org/10.1002/ams2.671
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author Sasaki, Kazuma
Obinata, Hirofumi
Yokobori, Shoji
Sakamoto, Taigo
author_facet Sasaki, Kazuma
Obinata, Hirofumi
Yokobori, Shoji
Sakamoto, Taigo
author_sort Sasaki, Kazuma
collection PubMed
description AIM: Alcohol‐related problems, including trauma, are a great burden on global health. Alcohol metabolism in the Japanese population is genetically inferior to other races. This study aimed to evaluate the effects of alcohol use among a Japanese severe blunt trauma cohort. METHODS: This retrospective observational study analyzed the data of trauma patients registered in the Japan Trauma Data Bank between 2004 and 2019. The primary outcome of this study was in‐hospital mortality. The lengths of hospital and intensive care unit stay were the secondary outcomes. Propensity score matching was used to adjust the anatomical severity and patient background to reduce the potential alcohol use bias. RESULTS: We analyzed 46,361 patients categorized into nondrinking (n = 37,818) and drinking (n = 8,543) groups. After a 1:1 propensity score matching (n = 8,428, respectively), despite the Glasgow Coma Scale and Revised Trauma Score scores being significantly lower in the drinking group (14 vs. 13 and 7.84 vs. 7.55, P < 0.001, respectively) and intensive care unit length of stay being significantly longer in the drinking group (6 vs. 7 days, P = 0.002), in‐hospital mortality was significantly lower in the alcohol group (11.8% vs. 9.0%, P < 0.001) and there were no differences in the duration of hospital stay (19 vs. 19 days, P = 0.848). CONCLUSION: Despite increasing physiological severity on admission, after adjusting for anatomical severity, alcohol consumption could be beneficial in severe blunt trauma patients as regards in‐hospital mortality.
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spelling pubmed-82546512021-07-13 Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank Sasaki, Kazuma Obinata, Hirofumi Yokobori, Shoji Sakamoto, Taigo Acute Med Surg Original Articles AIM: Alcohol‐related problems, including trauma, are a great burden on global health. Alcohol metabolism in the Japanese population is genetically inferior to other races. This study aimed to evaluate the effects of alcohol use among a Japanese severe blunt trauma cohort. METHODS: This retrospective observational study analyzed the data of trauma patients registered in the Japan Trauma Data Bank between 2004 and 2019. The primary outcome of this study was in‐hospital mortality. The lengths of hospital and intensive care unit stay were the secondary outcomes. Propensity score matching was used to adjust the anatomical severity and patient background to reduce the potential alcohol use bias. RESULTS: We analyzed 46,361 patients categorized into nondrinking (n = 37,818) and drinking (n = 8,543) groups. After a 1:1 propensity score matching (n = 8,428, respectively), despite the Glasgow Coma Scale and Revised Trauma Score scores being significantly lower in the drinking group (14 vs. 13 and 7.84 vs. 7.55, P < 0.001, respectively) and intensive care unit length of stay being significantly longer in the drinking group (6 vs. 7 days, P = 0.002), in‐hospital mortality was significantly lower in the alcohol group (11.8% vs. 9.0%, P < 0.001) and there were no differences in the duration of hospital stay (19 vs. 19 days, P = 0.848). CONCLUSION: Despite increasing physiological severity on admission, after adjusting for anatomical severity, alcohol consumption could be beneficial in severe blunt trauma patients as regards in‐hospital mortality. John Wiley and Sons Inc. 2021-07-03 /pmc/articles/PMC8254651/ /pubmed/34262778 http://dx.doi.org/10.1002/ams2.671 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Sasaki, Kazuma
Obinata, Hirofumi
Yokobori, Shoji
Sakamoto, Taigo
Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title_full Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title_fullStr Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title_full_unstemmed Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title_short Alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the Japan Trauma Data Bank
title_sort alcohol does not increase in‐hospital mortality due to severe blunt trauma: an analysis of propensity score matching using the japan trauma data bank
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254651/
https://www.ncbi.nlm.nih.gov/pubmed/34262778
http://dx.doi.org/10.1002/ams2.671
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