Cargando…
Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells
PURPOSE: Ephrin (Eph) receptor A2 (EPHA2) polymorphism has been associated with age-related cataract (ARC) in different populations worldwide, but the mechanisms by which this polymorphism results in the development of ARC are unclear. Here, we chose four EPHA2 single nucleotide polymorphisms (SNPs;...
Autores principales: | Li, Dan, Han, Xiaoyan, Zhao, Zhennan, Lu, Yi, Yang, Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254660/ https://www.ncbi.nlm.nih.gov/pubmed/34267496 |
Ejemplares similares
-
Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells
por: Li, Dan, et al.
Publicado: (2021) -
Screening and structural evaluation of deleterious Non-Synonymous SNPs of ePHA2 gene involved in susceptibility to cataract formation
por: Masoodi, Tariq Ahmad, et al.
Publicado: (2012) -
Structure analysis of deleterious nsSNPs in human PALB2 protein for functional inference
por: Nawar, Noshin, et al.
Publicado: (2021) -
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
por: Dobson, Richard J, et al.
Publicado: (2006) -
Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells
por: Zhao, Zhennan, et al.
Publicado: (2022)