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UHPLC-QQQ-MS/MS assay for the quantification of dianthrones as potential toxic markers of Polygonum multiflorum Thunb: applications for the standardization of traditional Chinese medicines (TCMs) with endogenous toxicity
BACKGROUND: The raw and processed roots of Polygonum multiflorum Thunb (PM) are commonly used in clinical practice to treat diverse diseases; however, reports of hepatotoxicity induced by Polygoni Multiflori Radix (PMR) and Polygoni Multiflori Radix Praeparata (PMRP) have emerged worldwide. Thus, it...
Autores principales: | Yang, Jian-Bo, Song, Yun-Fei, Liu, Yue, Gao, Hui-Yu, Wang, Qi, Wang, Ying, Cheng, Xian-Long, Zuo, Tian-Tian, Hu, Xiao-Wen, Wei, Feng, Jin, Hong-Tao, Wang, Shu-Ting, Ma, Shuang-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254911/ https://www.ncbi.nlm.nih.gov/pubmed/34217329 http://dx.doi.org/10.1186/s13020-021-00463-w |
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